The central nervous system (CNS) largely comprises nonregenerating cells, including
neurons and myelin-producing oligodendrocytes, which are particularly vulnerable to …

Modern high-throughput experiments provide us with numerous potential associations
between genes and diseases. Experimental validation of all the discovered associations, let …

To identify genes and biologically relevant pathways associated with risk to develop multiple
sclerosis (MS), the Genome-Wide Association Studies noise reduction method (GWAS-NR) …

Androgenetic alopecia (AGA) is a highly heritable condition, and the most common form of
hair loss in men. The phenotype is characterized by an androgen‐dependent, progressive …

The mechanisms of endotoxin tolerance (ET), which down-regulate inflammation, are well
described in response to exogenous toll-like receptor ligands, but few studies have focused …

Ankylosing spondylitis (AS) is an insidious and debilitating form of arthritis that involves the
axial skeleton, and its etiology and pathogenesis remain unclear. In the present study, three …

Background In order to retrieve useful information from scientific literature and electronic
medical records (EMR) we developed an ontology specific for Multiple Sclerosis (MS) …

Up to 50% of multiple sclerosis (MS) patients do not respond to interferon-beta (IFN-β)
treatment and determination of response requires lengthy clinical follow-up of up to 2 years …

Background Multiple sclerosis (MS) is a complex disease in which the immune system
attacks the central nervous system. The molecular mechanisms contributing to the etiology …

Background and purpose Nabiximols (Sativex®) is a cannabinoid‐based compound used
for the treatment of moderate to severe spasticity in multiple sclerosis (MS). The aim of the …