[HTML][HTML] Mesenchymal stromal cells: putative microenvironmental modulators become cell therapy
M Krampera, K Le Blanc - Cell stem cell, 2021 - cell.com
An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …
The therapeutic potential of mesenchymal stromal cells for regenerative medicine: current knowledge and future understandings
M Merimi, R El-Majzoub, L Lagneaux… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent decades, research on the therapeutic potential of progenitor cells has advanced
considerably. Among progenitor cells, mesenchymal stromal cells (MSCs) have attracted …
considerably. Among progenitor cells, mesenchymal stromal cells (MSCs) have attracted …
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages
How the innate and adaptive host immune system miscommunicate to worsen COVID-19
immunopathology has not been fully elucidated. Here, we perform single-cell deep-immune …
immunopathology has not been fully elucidated. Here, we perform single-cell deep-immune …
[HTML][HTML] Single-cell RNA landscape of the osteoimmunology microenvironment in periodontitis
Y Chen, H Wang, Q Yang, W Zhao, Y Chen, Q Ni… - Theranostics, 2022 - ncbi.nlm.nih.gov
Single-cell RNA sequencing (scRNA-seq) enables specific profiling of cell populations at
single-cell resolution. The osteoimmunology microenvironment in the occurrence and …
single-cell resolution. The osteoimmunology microenvironment in the occurrence and …
Clustering of single-cell multi-omics data with a multimodal deep learning method
Single-cell multimodal sequencing technologies are developed to simultaneously profile
different modalities of data in the same cell. It provides a unique opportunity to jointly …
different modalities of data in the same cell. It provides a unique opportunity to jointly …
Current perspectives on mesenchymal stromal cell therapy for graft versus host disease
Graft versus host disease (GvHD) is the clinical condition in which bone marrow-derived
mesenchymal stromal cells (MSCs) have been most frequently studied. In this review, we …
mesenchymal stromal cells (MSCs) have been most frequently studied. In this review, we …
Identifying the therapeutic significance of mesenchymal stem cells
The pleiotropic behavior of mesenchymal stem cells (MSCs) has gained global attention due
to their immense potential for immunosuppression and their therapeutic role in immune …
to their immense potential for immunosuppression and their therapeutic role in immune …
Therapeutic mesenchymal stem/stromal cells: value, challenges and optimization
M Najar, R Melki, F Khalife, L Lagneaux… - Frontiers in cell and …, 2022 - frontiersin.org
Cellular therapy aims to replace damaged resident cells by restoring cellular and molecular
environments suitable for tissue repair and regeneration. Among several candidates …
environments suitable for tissue repair and regeneration. Among several candidates …
Key strategies for clinical management and improvement of healthcare services for cardiovascular disease and diabetes patients in the coronavirus (COVID-19) …
Patients with cardiovascular disease and diabetes are at potentially higher risk of infection
and fatality due to COVID-19. Given the social and economic costs associated with disability …
and fatality due to COVID-19. Given the social and economic costs associated with disability …
Biomimetic approaches for targeting tumor-promoting inflammation
With the ultimate goal of increasing tumor accumulation of therapeutics, various
nanocarriers have been designed to overcome biological barriers encountered at each …
nanocarriers have been designed to overcome biological barriers encountered at each …