A review on chikungunya virus epidemiology, pathogenesis and current vaccine development

TYV de Lima Cavalcanti, MR Pereira, SO de Paula… - Viruses, 2022 - mdpi.com
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that recently re-emerged in
many parts of the world causing large-scale outbreaks. CHIKV infection presents as a febrile …

Zika virus

D Musso, DJ Gubler - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) in the genus Flavivirus and the
family Flaviviridae. ZIKV was first isolated from a nonhuman primate in 1947 and from …

[HTML][HTML] Global expansion of chikungunya virus: mapping the 64-year history

B Wahid, A Ali, S Rafique, M Idrees - International Journal of Infectious …, 2017 - Elsevier
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that is emerging as a
global threat because of the highly debilitating nature of the associated disease and …

The neurological complications of chikungunya virus: A systematic review

R Mehta, P Gerardin, CAA de Brito… - Reviews in medical …, 2018 - Wiley Online Library
We performed a systematic review on the neurological complications of chikungunya virus.
Such complications are being reported increasingly, owing primarily to the scale of recent …

Chikungunya virus infection: molecular biology, clinical characteristics, and epidemiology in Asian countries

S Khongwichit, J Chansaenroj, C Chirathaworn… - Journal of Biomedical …, 2021 - Springer
Chikungunya virus (CHIKV) is a re-emerging mosquito-borne human pathogen that causes
chikungunya fever, which is typically accompanied by severe joint pain. In Asia, serological …

Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial

LJ Chang, KA Dowd, FH Mendoza, JG Saunders… - The Lancet, 2014 - thelancet.com
Background Chikungunya virus—a mosquito-borne alphavirus—is endemic in Africa and
south and southeast Asia and has recently emerged in the Caribbean. No drugs or vaccines …

A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice

TH Teo, FM Lum, C Claser, V Lulla, A Lulla… - The Journal of …, 2013 - journals.aai.org
Chikungunya virus (CHIKV) is an alphavirus that causes chronic and incapacitating
arthralgia in humans. Injury to the joint is believed to occur because of viral and host …

Neuroinvasion and inflammation in viral central nervous system infections

T Dahm, H Rudolph, C Schwerk… - Mediators of …, 2016 - Wiley Online Library
Neurotropic viruses can cause devastating central nervous system (CNS) infections,
especially in young children and the elderly. The blood‐brain barrier (BBB) and the blood …

Chikungunya virus: pathophysiology, mechanism, and modeling

VK Ganesan, B Duan, SP Reid - Viruses, 2017 - mdpi.com
Chikungunya virus (CHIKV), a mosquito-transmitted alphavirus, is recurring in epidemic
waves. In the past decade and a half, the disease has resurged in several countries around …

Multiple immune factors are involved in controlling acute and chronic chikungunya virus infection

YS Poo, PA Rudd, J Gardner, JAC Wilson… - PLoS neglected …, 2014 - journals.plos.org
The recent epidemic of the arthritogenic alphavirus, chikungunya virus (CHIKV) has
prompted a quest to understand the correlates of protection against virus and disease in …