Lacunar stroke: mechanisms and therapeutic implications

S Yaghi, E Raz, D Yang, S Cutting… - Journal of Neurology …, 2021 - jnnp.bmj.com
Lacunar stroke is a marker of cerebral small vessel disease and accounts for up to 25% of
ischaemic stroke. In this narrative review, we provide an overview of potential lacunar stroke …

Platelet glycoprotein IIb/IIIa receptor inhibitor tirofiban in acute ischemic stroke

M Yang, X Huo, Z Miao, Y Wang - Drugs, 2019 - Springer
Tirofiban is a non-peptide selective glycoprotein (GP) IIb/IIIa receptor inhibitor that reversibly
inhibits fibrinogen-dependent platelet aggregation and subsequent formation of thrombi …

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies

D Wilson, G Ambler, KJ Lee, JS Lim… - The Lancet …, 2019 - thelancet.com
Background Cerebral microbleeds are a neuroimaging biomarker of stroke risk. A crucial
clinical question is whether cerebral microbleeds indicate patients with recent ischaemic …

Association of ischemic stroke onset time with presenting severity, acute progression, and long-term outcome: a cohort study

WS Ryu, KS Hong, SW Jeong, JE Park, BJ Kim… - PLoS …, 2022 - journals.plos.org
Background Preclinical data suggest circadian variation in ischemic stroke progression, with
more active cell death and infarct growth in rodent models with inactive phase (daytime) …

Stroke outcomes are worse with larger leukoaraiosis volumes

WS Ryu, SH Woo, D Schellingerhout, MU Jang… - Brain, 2017 - academic.oup.com
Leukoaraiosis or white matter hyperintensities are frequently observed on magnetic
resonance imaging of stroke patients. We investigated how white matter hyperintensity …

Branch atheromatous disease: a clinically meaningful, yet unproven concept

L Petrone, S Nannoni, A Del Bene, V Palumbo… - Cerebrovascular …, 2016 - karger.com
Abstract Background: In 1989, Louis Caplan first used the term branch atheromatous
disease (BAD) to describe an occlusion or stenosis at the origin of a deep penetrating artery …

Blood pressure variability and the development of early neurological deterioration following acute ischemic stroke

JW Chung, N Kim, J Kang, SH Park, WJ Kim… - Journal of …, 2015 - journals.lww.com
Objectives: Early neurological deterioration (END) is a common condition associated with
poor outcome after acute ischemic stroke. We studied association between blood pressure …

Different predictive factors for early neurological deterioration based on the location of single subcortical infarction: early prognosis in single subcortical infarction

KW Nam, HM Kwon, YS Lee - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Patients with single subcortical infarctions (SSIs) have relatively a
favorable prognosis, but they often experience early neurological deterioration (END). In this …

D‐dimer as a predictor of early neurologic deterioration in cryptogenic stroke with active cancer

KW Nam, CK Kim, TJ Kim, SJ An… - European journal of …, 2017 - Wiley Online Library
Background and purpose The occurrence of stroke in cancer patients is caused by
conventional vascular risk factors and cancer‐specific mechanisms. However, cryptogenic …

The validity and reliability of Korean frailty index

HS Hwang, IS Kwon, BJ Park, B Cho, JL Yoon… - Journal of the Korean …, 2010 - e-agmr.org
BACKGROUND Frailty is a syndrome that involves decreased reserve capacity and loss of
physiological function caused by aging. This study was done to develop a frailty index for the …