Background Methotrexate is considered the preferred disease‐modifying anti‐rheumatic
drug (DMARD) for the treatment of rheumatoid arthritis, but controversy exists on the …

The joint cavity constitutes a discrete anatomical compartment that allows for local drug
action after intra‐articular injection. Drug delivery systems providing local prolonged drug …

Objectives To compare mortality risks in patients with rheumatoid arthritis-associated
interstitial lung disease (RA-ILD) and patients with RA without ILD. Design Matched cohort …

Objectives: To develop evidence-based recommendations for the use of methotrexate in
daily clinical practice in rheumatic disorders. Methods: 751 rheumatologists from 17 …

Objective: To identify predictors of radiographic progression in a 2-year randomised, double-
blind, clinical study (CIMESTRA) of patients with early rheumatoid arthritis (RA). Methods …

R. Luqmani 1, S. Hennell 2, C. Estrach 3, F. Birrell 4, A. Bosworth 5, G. Davenport 6, C.
Fokke 7, N. Goodson 3, P. Jeffreson 8, E. Lamb 9, R. Mohammed 10, S. Oliver 11, Z …

Objectives Combining disease-modifying antirheumatic drugs (DMARDs) with
glucocorticoids (GCs) is an effective treatment strategy for early rheumatoid arthritis (ERA) …

Objective At 5 years' follow-up of early (< 6 months) rheumatoid arthritis patients to (1)
investigate whether initial combination therapy with methotrexate (MTX) and ciclosporin …

Rheumatoid arthritis is a common autoimmune disease primarily manifesting as chronic
synovitis, subsequently leading to a change in joint integrity. Progressive disability and …

The aim of the present study was to assess ultrasonography (US) for the detection of
inflammatory and destructive changes in finger and toe joints, tendons, and entheses in …