Recent advances in 3-aminoindazoles as versatile synthons for the synthesis of nitrogen heterocycles

Y Guo, Q Gao - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
Nitrogen-based heterocycles are an important class of structural scaffolds distributed in
biologically active natural products, medicinal chemistry, and agrochemicals. Hence, there is …

Synthesis of Imidazo[1,2-a]pyridine-Fused 1,3-Benzodiazepine Derivatives with Anticancer Activity via a One-Pot Cascade GBB-3CR/Pd(II)-Catalyzed Azide …

CR Zhong, YH Zhang, G Yao, HL Zhu… - The Journal of …, 2023 - ACS Publications
A new one-pot synthesis of imidazo [1, 2-a] pyridine-fused 1, 3-benzodiazepine derivatives
via a sequential GBB-3CR/Pd (II)-catalyzed azide-isocyanide coupling/cyclization process …

The Groebke–Blackburn–Bienaymé reaction in its maturity: innovation and improvements since its 21st birthday (2019–2023)

C Martini, MID Mardjan, A Basso - Beilstein Journal of Organic …, 2024 - beilstein-journals.org
Abstract The Groebke–Blackburn–Bienaymé (GBB) three-component reaction, discovered in
1998, is a very efficient strategy to assemble imidazo [1, 2-a]-heterocycles starting from …

Divergent synthesis of pyrrolidone fused pyrimido [1, 2-b] indazole through selective trapping of an enone intermediate by 1 H-indazol-3-amine

X Shen, ZC Yu, Y Zhou, YD Wu, AX Wu - Chemical Communications, 2024 - pubs.rsc.org
An oxidant-controlled divergent synthesis of a pyrrolidone fused pyrimido [1, 2-b] indazole
skeleton was developed through selective cyclization of an in situ generated enone …

Copper-catalyzed cross coupling reaction of sulfonyl hydrazides with 3-aminoindazoles

G Feng, J Meng, S Xu, Y Gao, Y Zhu, Z Huang - RSC advances, 2022 - pubs.rsc.org
A novel Cu-catalyzed radical–radical cross coupling reaction of 3-aminoindazoles with
sulfonyl hydrazides has been disclosed, enabling the production of diverse 1, 3-substituted …

Heterocycles as inputs in MCRs: An update

O Ghashghaei, M Pedrola, C Escolano… - Multicomponent …, 2022 - Wiley Online Library
Multicomponent reactions have great impact on modern organic synthesis. However, the
use of heterocycles as reactants in these processes is less developed. In this review, the …

Five-membered ring systems: with more than one N atom

L Yet - Progress in Heterocyclic Chemistry, 2021 - Elsevier
Five-membered ring systems: with more than one N atom - ScienceDirect Skip to main
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Improved Preparative Chemical Methodologies to Address Challenging Targets: Synthetic, Semi-synthetic and Multicomponent Approaches

M Pedrola Teixell - 2022 - diposit.ub.edu
[eng] In the context of facilitated methodologies for the obtention of bioactive compounds, in
this thesis we have explored the possibility of introducing reliable, pot-economic and semi …