Epigenetic underpinnings of inflammation: a key to unlock the tumor microenvironment in glioblastoma

N Chen, C Peng, D Li - Frontiers in Immunology, 2022 - frontiersin.org
Glioblastoma (GBM) is the most common malignant brain tumor in adults, and
immunotherapies and genetic therapies for GBM have evolved dramatically over the past …

Emerging roles of ferroptosis in glioma

J Shi, N Yang, M Han, C Qiu - Frontiers in Oncology, 2022 - frontiersin.org
Glioma is the most common primary malignant tumor in the central nervous system, and
directly affects the quality of life and cognitive function of patients. Ferroptosis, is a new form …

PRMT1 driven PTX3 regulates ferritinophagy in glioma

K Lathoria, P Gowda, SB Umdor, S Patrick, V Suri… - Autophagy, 2023 - Taylor & Francis
Mutations in the Krebs cycle enzyme IDH1 (isocitrate dehydrogenase (NADP (+)) 1) are
associated with better prognosis in gliomas. Though IDH1 mutant (IDH1R132H) tumors are …

[HTML][HTML] Targeting USP9X–AMPK axis in ARID1A-Deficient hepatocellular carcinoma

FK Zhang, QZ Ni, K Wang, HJ Cao, DX Guan… - Cellular and Molecular …, 2022 - Elsevier
Background & Aims Hepatocellular carcinoma (HCC) is a highly heterogeneous solid tumor
with high morbidity and mortality. AT-rich interaction domain 1A (ARID1A) accounts for up to …

Brg1 mutation alters oxidative stress responses in glioblastoma

P Gowda, K Lathoria, SB Umdor, E Sen - Neurochemistry International, 2021 - Elsevier
Increasing evidences suggest that the SWI/SNF chromatin remodeling complex involved in
the organization of chromatin architecture via ATP hydrolysis, plays an important role in …

Sustained correction of hippocampal neurogenic and cognitive deficits after a brief treatment by Nutlin-3 in a mouse model of fragile X syndrome

S Javadi, Y Li, J Sheng, L Zhao, Y Fu, D Wang, X Zhao - BMC medicine, 2022 - Springer
Abstract Background Fragile X syndrome (FXS), the most prevalent inherited intellectual
disability and one of the most common monogenic forms of autism, is caused by a loss of …