Compulsive behaviors are driven by repetitive urges and typically involve the experience of
limited voluntary control over these urges, a diminished ability to delay or inhibit these …

Medications, psychotherapy, and other treatments are effective for many patients with
psychiatric disorders. However, with currently available interventions, a substantial number …

Over the last few decades, advances in human and animal‐based techniques have greatly
enhanced our understanding of the neural mechanisms underlying psychiatric disorders …

Circuit dysfunction models of psychiatric disease posit that pathological behavior results
from abnormal patterns of electrical activity in specific cells and circuits in the brain. Many …

Restricted, repetitive behaviors (RRBs) are heterogeneous ranging from stereotypic body
movements to rituals to restricted interests. RRBs are most strongly associated with autism …

Over the last decades, extensive basic and clinical knowledge has been acquired on the
use of subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson's disease …

During treatment with deep brain stimulation (DBS), electrical current is delivered into the
brain parenchyma through implanted electrodes. Although this technique is routinely used in …

During the last 30 years there have been many attempts to develop animal models of
obsessive-compulsive disorder (OCD). Most models have not been studied further following …

Obsessive–compulsive disorder (OCD) is a disabling and common neuropsychiatric
condition of poorly known etiology. Many attempts have been made in the last few years to …

Deep brain stimulation (DBS) has proven to be capable of providing significant benefits for
several neuropathologies. It is highly effective in reducing the motor symptoms of …