Therapeutic targets, novel drugs, and delivery systems for diabetes associated NAFLD and liver fibrosis

V Kumar, X Xin, J Ma, C Tan, N Osna… - Advanced drug delivery …, 2021 - Elsevier
Type 2 diabetes mellitus (T2DM) associated non-alcoholic fatty liver disease (NAFLD) is the
fourth-leading cause of death. Hyperglycemia induces various complications, including …

[HTML][HTML] Gut microbiota diversity according to dietary habits and geographical provenance

B Senghor, C Sokhna, R Ruimy, JC Lagier - Human Microbiome Journal, 2018 - Elsevier
The gut microbiota is an ecosystem including all bacterial species that permanently colonize
the gastro intestinal tract and a large number of other microorganisms from the environment …

Insights into the epidemiology, pathogenesis, and therapeutics of nonalcoholic fatty liver diseases

Y Yu, J Cai, Z She, H Li - Advanced Science, 2019 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease which affects≈
25% of the adult population worldwide, placing a tremendous burden on human health. The …

Non-alcoholic fatty liver disease (NAFLD), type 2 diabetes, and non-viral hepatocarcinoma: Pathophysiological mechanisms and new therapeutic strategies

E Vetrano, L Rinaldi, A Mormone, C Giorgione… - Biomedicines, 2023 - mdpi.com
In recent years, the incidence of non-viral hepatocellular carcinoma (HCC) has increased
dramatically, which is probably related to the increased prevalence of metabolic syndrome …

Fructose: a dietary sugar in crosstalk with microbiota contributing to the development and progression of non-alcoholic liver disease

J Lambertz, S Weiskirchen, S Landert… - Frontiers in …, 2017 - frontiersin.org
Fructose is one of the key dietary catalysts in the development of non-alcoholic fatty liver
disease (NAFLD). NAFLD comprises a complex disease spectrum, including steatosis (fatty …

A critical review on health promoting benefits of edible mushrooms through gut microbiota

M Jayachandran, J Xiao, B Xu - International journal of molecular …, 2017 - mdpi.com
Mushrooms have long been used for medicinal and food purposes for over a thousand
years, but a complete elucidation of the health-promoting properties of mushrooms through …

Therapeutic potential and nutritional significance of Ganoderma lucidum–a comprehensive review from 2010 to 2022

MS Swallah, P Bondzie-Quaye, Y Wu… - Food & function, 2023 - pubs.rsc.org
With a long history in traditional Asian medicine, Ganoderma lucidum (G. lucidum) is a
mushroom species suggested to improve health and extend life. Its medicinal reputation has …

[HTML][HTML] Metabolic aspects of adult patients with nonalcoholic fatty liver disease

L Abenavoli, N Milic, L Di Renzo… - World journal of …, 2016 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease and it
encompasses a spectrum from simple steatosis to steatohepatitis, fibrosis, or cirrhosis. The …

Inflammation initiates a vicious cycle between obesity and nonalcoholic fatty liver disease

Y Luo, H Lin - Immunity, Inflammation and Disease, 2021 - Wiley Online Library
Low‐level of chronic inflammation activation is characteristic of obesity. Nonalcoholic fatty
liver disease (NAFLD) is closely linked to obesity and is an emerging health problem, it …

Perspectives on precision medicine approaches to NAFLD diagnosis and management

A Lonardo, JP Arab, M Arrese - Advances in Therapy, 2021 - Springer
Precision medicine defines the attempt to identify the most effective approaches for specific
subsets of patients based on their genetic background, clinical features, and environmental …