Toxicity in the era of immune checkpoint inhibitor therapy
S Keam, N Turner, FG Kugeratski, R Rico… - Frontiers in …, 2024 - frontiersin.org
Immune checkpoint inhibitors (ICIs) reinvigorate anti-tumor immune responses by disrupting
co-inhibitory immune checkpoint molecules such as programmed cell death 1 (PD-1) and …
co-inhibitory immune checkpoint molecules such as programmed cell death 1 (PD-1) and …
Immune-mediated colitis after immune checkpoint inhibitor therapy
S Giesler, R Riemer, T Lowinus, R Zeiser - Trends in Molecular Medicine, 2024 - cell.com
Immune checkpoint inhibitors (ICIs) have led to improved outcome in patients with various
types of cancer. Due to inhibition of physiological anti-inflammatory mechanisms, patients …
types of cancer. Due to inhibition of physiological anti-inflammatory mechanisms, patients …
Immune Checkpoint Inhibitors as First-line Treatment for Brain Metastases in Stage IV NSCLC Patients without Driver Mutations
G Suay, JC Garcia-Cañaveras, F Aparisi, J Garcia… - Cancer Letters, 2024 - Elsevier
Immune checkpoint inhibitors (ICI) therapy with or without chemotherapy has been
established as the first-line treatment for patients with non-oncogene addicted advanced …
established as the first-line treatment for patients with non-oncogene addicted advanced …
Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function
OV Ifejeokwu, AH Do, SM El-Khatib, NH Ho, A Zavala… - bioRxiv, 2024 - biorxiv.org
Combinatorial blockade of Cytotoxic T-lymphocyte associated protein 4 (CTLA-4) and
Programmed Cell Death Protein 1 (PD-1) significantly improve the progression-free survival …
Programmed Cell Death Protein 1 (PD-1) significantly improve the progression-free survival …
The Contribution of the Monocyte‐Macrophage Lineage to Immunotherapy Outcomes
RC Adams, KPA MacDonald, GR Hill - Blood, 2024 - Elsevier
Macrophages execute core functions in maintaining tissue homeostasis, where their
extensive plasticity permits a spectrum of functions from tissue remodelling to immune …
extensive plasticity permits a spectrum of functions from tissue remodelling to immune …
Advances in cell therapy: progress and challenges in hematological and solid tumors
C D'Avanzo, F Blaeschke, M Lysandrou… - Trends in …, 2024 - cell.com
Cell-based therapies harness the endogenous ability of the immune system to fight cancer
and have shown promising results in the treatment of hematological malignancies. However …
and have shown promising results in the treatment of hematological malignancies. However …
Boosting peripheral immunity to fight neurodegeneration in the brain
M Schwartz, SP Colaiuta - Trends in Immunology, 2024 - cell.com
Reciprocal communication between the brain and the immune system is essential for
maintaining lifelong brain function. This interaction is mediated, at least in part, by immune …
maintaining lifelong brain function. This interaction is mediated, at least in part, by immune …