Exercise improves clinical symptoms, quality of life, global functioning, and depression in schizophrenia: a systematic review and meta-analysis

M Dauwan, MJH Begemann, SM Heringa… - Schizophrenia …, 2016 - academic.oup.com
Background: Physical exercise may be valuable for patients with schizophrenia spectrum
disorders as it may have beneficial effect on clinical symptoms, quality of life and cognition …

[HTML][HTML] The relationship between cognition and functioning in schizophrenia: a semi-systematic review

S Kharawala, C Hastedt, J Podhorna, H Shukla… - Schizophrenia Research …, 2022 - Elsevier
In schizophrenia, impairments in neurocognition (NC) and social cognition (SC) are
associated with reduced functional capacity (FC) and poor real-world functioning (RWF). In …

Factors associated with real-life functioning in persons with schizophrenia in a 4-year follow-up study of the Italian network for research on psychoses

A Mucci, S Galderisi, D Gibertoni, A Rossi… - JAMA …, 2021 - jamanetwork.com
Importance The goal of schizophrenia treatment has shifted from symptom reduction and
relapse prevention to functional recovery; however, recovery rates remain low. Prospective …

Interplay among psychopathologic variables, personal resources, context-related factors, and real-life functioning in individuals with schizophrenia: a network analysis

S Galderisi, P Rucci, B Kirkpatrick, A Mucci… - JAMA …, 2018 - jamanetwork.com
Importance Enhanced understanding of factors associated with symptomatic and functional
recovery is instrumental to designing personalized treatment plans for people with …

Efficacy and safety of the novel glycine transporter inhibitor BI 425809 once daily in patients with schizophrenia: a double-blind, randomised, placebo-controlled …

WW Fleischhacker, J Podhorna, M Gröschl… - The Lancet …, 2021 - thelancet.com
Background Cognitive impairment associated with schizophrenia predicts poor functional
outcomes, but currently no approved pharmacotherapy is available. This study investigated …

Rehabilitation interventions to promote recovery from schizophrenia: a systematic review

L Morin, N Franck - Frontiers in psychiatry, 2017 - frontiersin.org
Only one out of seven patients recovers after a first episode of psychosis despite psychiatric
care. Rehabilitation interventions have been developed to improve functional outcomes and …

Long-term changes in cognitive functioning in individuals with psychotic disorders: findings from the Suffolk County Mental Health Project

AKJ Fett, E Velthorst, A Reichenberg… - JAMA …, 2020 - jamanetwork.com
Importance It remains uncertain whether people with psychotic disorders experience
progressive cognitive decline or normal cognitive aging after first hospitalization. This …

Prediction of disability in schizophrenia: Symptoms, cognition, and self-assessment

PD Harvey, MT Strassnig… - Journal of Experimental …, 2019 - journals.sagepub.com
Schizophrenia is associated with wide-ranging disability across multiple functional domains.
There are several determinants of disability that have been identified to date, including …

Treatment resistant schizophrenia is associated with the worst community functioning among severely-ill highly-disabling psychiatric conditions and is the most …

F Iasevoli, S Giordano, R Balletta, G Latte… - Progress in Neuro …, 2016 - Elsevier
The aim of this work was to compare achievements in milestones of community functioning
in highly disabling psychiatric conditions, including treatment resistant schizophrenia (TRS) …

Avolition as the core negative symptom in schizophrenia: relevance to pharmacological treatment development

GP Strauss, LA Bartolomeo, PD Harvey - npj Schizophrenia, 2021 - nature.com
Negative symptoms have long been considered a core component of schizophrenia.
Modern conceptualizations of the structure of negative symptoms posit that there are at least …