Abstract Transcription factor 21 (TCF21) is a member of the basic helix-loop-helix (bHLH)
transcription factors that mediate cell fate and differentiation by orchestrating temporal and …

Transcription factor 21 (TCF21) is a basic helix–loop–helix transcription factor that binds to
DNA and regulates cell differentiation and cell fate specification through mesenchymal …

Nervous system malignancies are characterized by rapid progression and poor survival
rates. These clinical observations underscore the need for novel therapeutic insights and …

Purpose Nr5a2 (nuclear receptor subfamily 5 group A member 2, also known as LRH-1),
which belongs to the NR5A (Ftz-F1) subfamily of nuclear receptors, is a key regulator in stem …

Background Our initial genome-wide association study (GWAS) identified 20 promising
candidate genes for milk fatty acid (FA) traits in a Chinese Holstein population, including …

DNA methylation is a key transcription regulator, whose aberration was ubiquitous and
important in most cancers including hepatocellular carcinoma (HCC). Whole-genome …

Abstract Steroidogenic factor-1 (SF-1, encoded by NR5A1) and estrogen receptor beta
(ERβ, encoded by ESR2), which are highly expressed in endometriotic stromal cells (ESCs) …

Several prognostic indicators have shown inconsistencies in patients of different genders
with lung adenocarcinoma, indicating that these variations may be due to the different …

Abstract Transcription factor 21 (TCF21) directly binds and regulates SF1 mRNA expression
in tumor and normal adrenocortical cells, and both are involved in the development and …

OBJECTIVES: Transcription Factor 21 represses steroidogenic factor 1, a nuclear receptor
required for gonadal development, sex determination and the regulation of adrenogonadal …