TCF21: a critical transcription factor in health and cancer
X Ao, W Ding, Y Zhang, D Ding, Y Liu - Journal of Molecular Medicine, 2020 - Springer
Abstract Transcription factor 21 (TCF21) is a member of the basic helix-loop-helix (bHLH)
transcription factors that mediate cell fate and differentiation by orchestrating temporal and …
transcription factors that mediate cell fate and differentiation by orchestrating temporal and …
Multiple biological functions of transcription factor 21 in the development of various cancers
X Jiang, Z Yang - OncoTargets and therapy, 2018 - Taylor & Francis
Transcription factor 21 (TCF21) is a basic helix–loop–helix transcription factor that binds to
DNA and regulates cell differentiation and cell fate specification through mesenchymal …
DNA and regulates cell differentiation and cell fate specification through mesenchymal …
Nuclear receptor NR5A2 negatively regulates cell proliferation and tumor growth in nervous system malignancies
D Gkikas, D Stellas, A Polissidis… - Proceedings of the …, 2021 - National Acad Sciences
Nervous system malignancies are characterized by rapid progression and poor survival
rates. These clinical observations underscore the need for novel therapeutic insights and …
rates. These clinical observations underscore the need for novel therapeutic insights and …
Nr5a2 promotes tumor growth and metastasis of gastric cancer AGS cells by Wnt/beta-catenin signaling
L Liu, Y Li, B Pan, T Zhang, D Wei, Y Zhu… - OncoTargets and …, 2019 - Taylor & Francis
Purpose Nr5a2 (nuclear receptor subfamily 5 group A member 2, also known as LRH-1),
which belongs to the NR5A (Ftz-F1) subfamily of nuclear receptors, is a key regulator in stem …
which belongs to the NR5A (Ftz-F1) subfamily of nuclear receptors, is a key regulator in stem …
Polymorphisms and genetic effects of PRLR, MOGAT1, MINPP1 and CHUK genes on milk fatty acid traits in Chinese Holstein
L Shi, L Liu, X Lv, Z Ma, Y Yang, Y Li, F Zhao, D Sun… - BMC genetics, 2019 - Springer
Background Our initial genome-wide association study (GWAS) identified 20 promising
candidate genes for milk fatty acid (FA) traits in a Chinese Holstein population, including …
candidate genes for milk fatty acid (FA) traits in a Chinese Holstein population, including …
Integrative analysis of epigenome and transcriptome data reveals aberrantly methylated promoters and enhancers in hepatocellular carcinoma
P Huang, M Xu, H Han, X Zhao, MD Li, Z Yang - Frontiers in Oncology, 2021 - frontiersin.org
DNA methylation is a key transcription regulator, whose aberration was ubiquitous and
important in most cancers including hepatocellular carcinoma (HCC). Whole-genome …
important in most cancers including hepatocellular carcinoma (HCC). Whole-genome …
Transcription factor 21 regulates expression of ERβ and SF-1 via upstream stimulatory factor-2 in endometriotic tissues
PL Wu, Y Zhou, C Zeng, X Li, ZT Dong, YF Zhou… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Abstract Steroidogenic factor-1 (SF-1, encoded by NR5A1) and estrogen receptor beta
(ERβ, encoded by ESR2), which are highly expressed in endometriotic stromal cells (ESCs) …
(ERβ, encoded by ESR2), which are highly expressed in endometriotic stromal cells (ESCs) …
Prognostic significance of TCF21 mRNA expression in patients with lung adenocarcinoma
J Xiao, A Liu, X Lu, X Chen, W Li, S He, B He… - Scientific reports, 2017 - nature.com
Several prognostic indicators have shown inconsistencies in patients of different genders
with lung adenocarcinoma, indicating that these variations may be due to the different …
with lung adenocarcinoma, indicating that these variations may be due to the different …
N-type calcium channel v2. 2 is a target of TCF21 in adrenocortical carcinomas.
B dos Santos PASSAIA, JL Kremer… - …, 2022 - search.ebscohost.com
Abstract Transcription factor 21 (TCF21) directly binds and regulates SF1 mRNA expression
in tumor and normal adrenocortical cells, and both are involved in the development and …
in tumor and normal adrenocortical cells, and both are involved in the development and …
New evidences on the regulation of SF-1 expression by POD1/TCF21 in adrenocortical tumor cells
OBJECTIVES: Transcription Factor 21 represses steroidogenic factor 1, a nuclear receptor
required for gonadal development, sex determination and the regulation of adrenogonadal …
required for gonadal development, sex determination and the regulation of adrenogonadal …