Evolution and molecular epidemiology of polyomaviruses

C Torres - Infection, Genetics and Evolution, 2020 - Elsevier
Polyomaviruses (PyVs) are small DNA viruses that infect several species, including
mammals, birds and fishes. Their study gained momentum after the report of previously …

Regulation of polyomavirus transcription by viral and cellular factors

JF Yang, J You - Viruses, 2020 - mdpi.com
Polyomavirus infection is widespread in the human population. This family of viruses
normally maintains latent infection within the host cell but can cause a range of human …

Development of a therapeutic vaccine targeting Merkel cell polyomavirus capsid protein VP1 against Merkel cell carcinoma

D Xu, S Jiang, Y He, X Jin, G Zhao, B Wang - npj Vaccines, 2021 - nature.com
Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer with a high mortality rate,
while Merkel cell polyomavirus (MCV) has been pointed as the causative agent of MCC. A …

Prevalence and genetic variability of human polyomaviruses 6 and 7 in healthy skin among asymptomatic individuals

Y Hashida, T Higuchi, S Matsuzaki… - The Journal of …, 2018 - academic.oup.com
Background Despite the pathogenetic potential of human polyomavirus 6 (HPyV6) and
human polyomavirus 7 (HPyV7), they have been found in the normal skin of healthy …

Genetic variability of the noncoding control region of cutaneous Merkel cell polyomavirus: identification of geographically related genotypes

Y Hashida, T Higuchi, K Matsui… - The Journal of …, 2018 - academic.oup.com
Abstract Background Merkel cell polyomavirus (MCPyV) is a ubiquitous cutaneous virus that
causes Merkel cell carcinoma, which develops preferentially in white populations from …

Structural analysis of merkel cell polyomavirus (MCPyV) viral capsid protein 1 (VP1) in HIV-1 infected individuals

C Prezioso, M Bianchi, F Obregon, M Ciotti… - International Journal of …, 2020 - mdpi.com
Merkel cell polyomavirus (MCPyV) viral protein 1 (VP1) is the capsid protein that mediates
virus attachment to host cell receptors and is the major immune target. Given the limited data …

Phylodynamics of Merkel-cell polyomavirus and human polyomavirus 6: A long-term history with humans

C Torres, ME Barrios, RV Cammarata, M Victoria… - Molecular phylogenetics …, 2018 - Elsevier
New human polyomaviruses have been described in the last years, including the Merkel-cell
polyomavirus (MCPyV; Human polyomavirus 5) and the Human polyomavirus 6 (HPyV6) …

Human Polyomaviruses (HPyV) in Wastewater and Environmental Samples from the Lisbon Metropolitan Area: Detection and Genetic Characterization of Viral …

AC Condez, M Nunes, A Filipa-Silva, I Leonardo… - Pathogens, 2021 - mdpi.com
Due to the lack of reliable epidemiological information regarding the geographic distribution
and genetic diversity of human polyomaviruses (HPyV) in Portugal, we addressed these …

Merkel cell Polyomavirus (MCPyV) in non-Merkel Cell Carcinoma (non-MCC)

C Prezioso - 2023 - iris.uniroma1.it
Merkel cell polyomavirus (MCPyV) has been detected in respiratory specimens including
those from Cystic Fibrosis (CF) patients, raising questions about its immunological and …

Characterization of the Mechanisms Driving the Transcription and Tumorigenic Potential of Merkel Cell Polyomavirus

JF Yang - 2024 - search.proquest.com
Merkel cell carcinoma (MCC) is a rare and aggressive form of skin cancer that metastasizes
rapidly and resists most current therapies. Approximately 80% of MCC tumors are …