The Gateway® cloning system sets a new trend in molecular biology by addressing the
difficulties of adaptability, efficiency and compatibility of the traditional cloning approaches …

Detailed knowledge of the biochemistry and structure of individual proteins is fundamental to
biomedical research. To further our understanding, however, proteins need to be purified in …

Background The past few years have seen a vast increase in the amount of genomic data
available for a growing number of taxa, including sets of full length cDNA clones and cis …

A set of mutated Encephalomyocarditis virus (EMCV) internal ribosome entry site (IRES)
elements with varying strengths is generated by mutating the translation initiation codons of …

2015-11-19 Assigned to WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
reassignment WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH ASSIGNMENT OF …

Multi-protein complexes are involved in essentially all cellular processes. A protein's
function is defined by a combination of its own properties, its interacting partners, and the …

Nuclear factor-κB (NF-κB) is a core regulator in multiple tumorigenic pathways. Its activation
is mediated by IκB kinase β (IKKβ). Protein phosphatase PPM1B is reported to …

Bicistronic reporter assays have been instrumental for transgene expression, understanding
of internal ribosomal entry site (IRES) translation, and identification of novel cap …

Generation of DNA clones for use in proteomic and genomic research often requires a
significant level of parallel production, as the number of downstream options for these …

Molecular farming is an experimental application of biotechnology that involves the genetic
modification of crops for the production of proteins and chemicals for medicinal and …