The genesis of schizophrenia: an origin story

R Birnbaum, DR Weinberger - American Journal of Psychiatry, 2024 - Am Psychiatric Assoc
Schizophrenia is routinely referred to as a neurodevelopmental disorder, but the role of
brain development in a disorder typically diagnosed during early adult life is enigmatic. The …

From compartments to loops: understanding the unique chromatin organization in neuronal cells

D Zagirova, A Kononkova, N Vaulin… - Epigenetics & Chromatin, 2024 - Springer
The three-dimensional organization of the genome plays a central role in the regulation of
cellular functions, particularly in the human brain. This review explores the intricacies of …

[HTML][HTML] Sex differences in brain cell-type specific chromatin accessibility in schizophrenia

P Roussos, Y Ma, K Girdhar, G Hoffman… - Research …, 2024 - ncbi.nlm.nih.gov
Our understanding of the sex-specific role of the non-coding genome in serious mental
illness remains largely incomplete. To address this gap, we explored sex differences in …