Spinal interneurons are important facilitators and modulators of motor, sensory, and
autonomic functions in the intact CNS. This heterogeneous population of neurons is now …

Oxidative stress has been implicated in the etiology and pathobiology of various
neurodegenerative diseases. At baseline, the cells of the nervous system have the capability …

The mammalian spinal cord functions as a community of cell types for sensory processing,
autonomic control, and movement. While animal models have advanced our understanding …

Amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of somatic motor
neurons. A major focus has been directed to motor neuron intrinsic properties as a cause for …

Action selection is a capital feature of cognition that guides behavior in processes that range
from motor patterns to executive functions. Here, the ongoing actions need to be monitored …

Simple Summary Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease
affecting the motor neurons in the brain and spinal cord. Mutations in the gene Matr3 have …

The mechanisms underlying the loss of motor neuron axon integrity in amyotrophic lateral
sclerosis (ALS) are unclear. SARM1 has been identified as a genetic risk variant in sporadic …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that affects
upper and lower motor neurons and leads to death a few years after symptom onset. Despite …

Amyotrophic lateral sclerosis is a devastating neurodegenerative disease that, at present,
has no effective cure. Evidence of increased circulating glutamate and hyperexcitability of …

The rapidly growing field of cellular engineering is enabling scientists to more effectively
create in vitro models of disease and develop specific cell types that can be used to repair …