Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection

WR García-Niño, C Zazueta - Pharmacological Research, 2015 - Elsevier
Traditional drugs or therapies rarely have effects on regression of chronic liver diseases,
which result in many cases from sustained oxidative stress. In recent years, ellagic acid (EA) …

Update on the bioavailability and chemopreventative mechanisms of dietary chlorophyll derivatives

M Hayes, MG Ferruzzi - Nutrition research, 2020 - Elsevier
Chlorophyll, a phytochemical responsible for the green pigmentation in plants, has been
studied for almost 100 years for its biological activities in humans. Over the past 30 years …

A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer

M Goldberg, A Manzi, A Birdi, B Laporte… - Nature …, 2022 - nature.com
Despite therapeutic advancements, oral cavity squamous cell carcinoma (OCSCC) remains
a difficult disease to treat. Systemic platinum-based chemotherapy often leads to dose …

Role of ellagic acid for the prevention and treatment of liver diseases

V Aishwarya, S Solaipriya… - Phytotherapy …, 2021 - Wiley Online Library
Globally, one of the alarming problems is the prevalence and burden of liver diseases,
which accounts for 2 million cases per year. Chronic liver aetiologies such as hepatitis …

Ellagitannins in cancer chemoprevention and therapy

T Ismail, C Calcabrini, AR Diaz, C Fimognari, E Turrini… - Toxins, 2016 - mdpi.com
It is universally accepted that diets rich in fruit and vegetables lead to reduction in the risk of
common forms of cancer and are useful in cancer prevention. Indeed edible vegetables and …

Mouse tumor-bearing models as preclinical study platforms for oral squamous cell carcinoma

Q Li, H Dong, G Yang, Y Song, Y Mou, Y Ni - Frontiers in oncology, 2020 - frontiersin.org
Preclinical animal models of oral squamous cell carcinoma (OSCC) have been extensively
studied in recent years. Investigating the pathogenesis and potential therapeutic strategies …

Recent advances in anticancer activities and drug delivery systems of tannins

Y Cai, J Zhang, NG Chen, Z Shi, J Qiu… - Medicinal Research …, 2017 - Wiley Online Library
Tannins, polyphenols in medicinal plants, have been divided into two groups of
hydrolysable and condensed tannins, including gallotannins, ellagitannins, and (–) …

Plastids of marine phytoplankton produce bioactive pigments and lipids

P Heydarizadeh, I Poirier, D Loizeau, L Ulmann… - Marine drugs, 2013 - mdpi.com
Phytoplankton is acknowledged to be a very diverse source of bioactive molecules. These
compounds play physiological roles that allow cells to deal with changes of the …

Chemopreventive potential of chlorophyllin: a review of the mechanisms of action and molecular targets

S Nagini, F Palitti, AT Natarajan - Nutrition and cancer, 2015 - Taylor & Francis
Chlorophyllin (CHL), a water soluble semisynthetic derivative of the ubiquitous plant
pigment chlorophyll used as a food additive, is recognized to confer a wide range of health …

Association of cancer metabolism-related proteins with oral carcinogenesis–indications for chemoprevention and metabolic sensitizing of oral squamous cell …

M Grimm, M Cetindis, M Lehmann, T Biegner… - Journal of translational …, 2014 - Springer
Background Tumor metabolism is a crucial factor for the carcinogenesis of oral squamous
cell carcinoma (OSCC). Methods Expression of IGF-R1, glycolysis-related proteins (GLUT-1 …