Five decades later, are mesenchymal stem cells still relevant?

M Gomez-Salazar, ZN Gonzalez-Galofre… - … in bioengineering and …, 2020 - frontiersin.org
Mesenchymal stem cells are culture-derived mesodermal progenitors isolatable from all
vascularized tissues. In spite of multiple fundamental, pre-clinical and clinical studies, the …

Mesenchymal stem cells as a cornerstone in a galaxy of intercellular signals: basis for a new era of medicine

S Fernández-Francos, N Eiro, LA Costa… - International journal of …, 2021 - mdpi.com
Around 40% of the population will suffer at some point in their life a disease involving tissue
loss or an inflammatory or autoimmune process that cannot be satisfactorily controlled with …

Microfragmented adipose tissue versus platelet-rich plasma for the treatment of knee osteoarthritis: a prospective randomized controlled trial at 2-year follow-up

S Zaffagnini, L Andriolo, A Boffa… - … American Journal of …, 2022 - journals.sagepub.com
Background: Intra-articular microfragmented adipose tissue (MF-AT) injections have been
proposed for the treatment of knee osteoarthritis (OA). Purpose: To compare a single …

Mesenchymal stem cell therapy for ischemic stroke: a look into treatment mechanism and therapeutic potential

J Li, Q Zhang, W Wang, F Lin, S Wang, J Zhao - Journal of neurology, 2021 - Springer
Stroke, a global disease with a high disability rate, has limited options for functional
rehabilitation and results in an adverse impact on patients' lives. In recent years …

Therapeutic potential of adipose tissue‐derivatives in modern dermatology

B Bellei, E Migliano, M Picardo - Experimental Dermatology, 2022 - Wiley Online Library
Stem cell‐mediated therapies in combination with biomaterial and growth factor‐based
approaches in regenerative medicine are rapidly evolving with increasing application …

Aldehyde dehydrogenase, a marker of normal and malignant stem cells, typifies mesenchymal progenitors in perivascular niches

MA Gomez-Salazar, Y Wang… - Stem Cells …, 2023 - academic.oup.com
Innate mesenchymal stem cells exhibiting multilineage differentiation and tissue (re)
generative—or pathogenic—properties reside in perivascular niches. Subsets of these …

Micro-fragmented adipose tissue as a natural scaffold for targeted drug delivery in brain cancer

A Salagean, A Nechifor-Boila, N Bajwa… - International Journal of …, 2023 - mdpi.com
Major limitations in the effective treatment of neurological cancer include systemic
cytotoxicity of chemotherapy, inaccessibility, and inoperability. The capability to successfully …

Strategies to improve AFT volume retention after fat grafting

M Liu, Y Shang, N Liu, Y Zhen, Y Chen, Y An - Aesthetic Plastic Surgery, 2023 - Springer
Background Autologous fat grafting has gained increasing popularity used in plastic surgery
as a strategy to improve functional and aesthetic outcome. However, variable augmentation …

Injection Treatments for Vulvovaginal Atrophy of Menopause: A Systematic Review

F Moccia, P Pentangelo, A Ceccaroni, A Raffone… - Aesthetic Plastic …, 2023 - Springer
Background Injection treatments have been proposed as novel treatment options for
Vulvovaginal Atrophy of Menopause (VVA) also known as Genitourinary Syndrome of …

Cartilage Lesions and Osteoarthritis: Cell Therapy

TL Fernandes, K Shimomura, DA Hart, A Boffa… - … : Injectable Therapies for …, 2022 - Springer
Symptomatic cartilage lesions and early osteoarthritis (OA) are musculoskeletal issues with
both significant clinical and large economic burdens. Despite regenerative techniques, such …