Natural 5-aminolevulinic acid: Sources, biosynthesis, detection and applications
5-Aminolevulinic acid (5-ALA) is the key precursor for the biosynthesis of tetrapyrrole
compounds, with wide applications in medicine, agriculture and other burgeoning fields …
compounds, with wide applications in medicine, agriculture and other burgeoning fields …
A review: Molecular chaperone-mediated folding, unfolding and disaggregation of expressed recombinant proteins
K Fatima, F Naqvi, H Younas - Cell Biochemistry and Biophysics, 2021 - Springer
The advancements in biotechnology over time have led to an increase in the demand of
pure, soluble and functionally active proteins. Recombinant protein production has thus …
pure, soluble and functionally active proteins. Recombinant protein production has thus …
Electrochemical synthesis of glycine from oxalic acid and nitrate
In manufacturing C− N bond‐containing compounds, it is an important challenge to alternate
the conventional methodologies that utilize reactive substrates, toxic reagents, and organic …
the conventional methodologies that utilize reactive substrates, toxic reagents, and organic …
Enhanced recombinant carbonic anhydrase in T7RNAP-equipped Escherichia coli W3110 for carbon capture storage and utilization (CCSU)
Sulfurihydrogenibium yellowstonense carbonic anhydrase (SyCA) is a well-known
thermophilic CA for carbon mineralization. To broaden the applications of SyCA, the activity …
thermophilic CA for carbon mineralization. To broaden the applications of SyCA, the activity …
Strain engineering for high‐level 5‐aminolevulinic acid production in Escherichia coli
D Miscevic, JY Mao, T Kefale, D Abedi… - Biotechnology and …, 2021 - Wiley Online Library
Herein, we report the development of a microbial bioprocess for high‐level production of 5‐
aminolevulinic acid (5‐ALA), a valuable non‐proteinogenic amino acid with multiple …
aminolevulinic acid (5‐ALA), a valuable non‐proteinogenic amino acid with multiple …
Adaptive laboratory evolution and metabolic regulation of genetic Escherichia coli W3110 toward low-carbon footprint production of 5-aminolevulinic acid
Abstract Background The 5-aminolevulinic acid (5-ALA) is a prodrug that has been
approved by FDA for photodynamic therapy of cancer. 5-ALA is intracellularly metabolized to …
approved by FDA for photodynamic therapy of cancer. 5-ALA is intracellularly metabolized to …
Stepwise optimization of genetic RuBisCO-equipped Escherichia coli for low carbon-footprint protein and chemical production
Bio-mitigation of carbon dioxide has recently attracted more research focus because it is a
sustainable and ecofriendly way of carbon conversion to a variety of indispensable …
sustainable and ecofriendly way of carbon conversion to a variety of indispensable …
Biosynthesis, acquisition, regulation, and upcycling of heme: recent advances
Heme, an iron-containing tetrapyrrole in hemoproteins, including: hemoglobin, myoglobin,
catalase, cytochrome c, and cytochrome P450, plays critical physiological roles in different …
catalase, cytochrome c, and cytochrome P450, plays critical physiological roles in different …
Engineering pyridoxal kinase PdxY-integrated Escherichia coli strain and optimization for high-level 5-aminolevulinic acid production
C Xue, TH Yu, IS Ng - Journal of the Taiwan Institute of Chemical Engineers, 2021 - Elsevier
Abstract Recently, 5-aminolevulinic acid (ALA) has gained significant attention in research
due to its extensive applications in agriculture, aquaculture, cosmetics, and photodynamic …
due to its extensive applications in agriculture, aquaculture, cosmetics, and photodynamic …
Challenges and opportunities of bioprocessing 5-aminolevulinic acid using genetic and metabolic engineering: a critical review
Aminolevulinic acid (5-ALA), a non-proteinogenic five-carbon amino acid, has received
intensive attentions in medicine due to its approval by the US Food and Drug Administration …
intensive attentions in medicine due to its approval by the US Food and Drug Administration …