Retinitis Pigmentosa (RP) in the human is a progressive, currently irreversible neural
degenerative disease usually caused by gene defects that disrupt the function or …

The retina, like many other central nervous system structures, contains a huge diversity of
neuronal types. Mammalian retinas contain approximately 55 distinct cell types, each with a …

The retinal degenerative diseases, which together constitute a leading cause of hereditary
blindness worldwide, are largely untreatable. Development of reliable methods to culture …

This review summarizes our current knowledge of primate including human retina focusing
on bipolar, amacrine and ganglion cells and their connectivity. We have two main …

Mammalian retinal degenerations initiated by gene defects in rods, cones or the retinal
pigmented epithelium (RPE) often trigger loss of the sensory retina, effectively leaving the …

Many photoreceptor degenerations initially affect rods, secondarily leading to cone death. It
has long been assumed that the surviving neural retina is largely resistant to this sensory …

Lateral interactions in the outer retina, particularly negative feedback from horizontal cells to
cones and direct feed-forward input from horizontal cells to bipolar cells, play a number of …

We report a quantitative survey of the population of amacrine cells present in the retina of
the rabbit. The cells' dendritic shape and level of stratification were visualized by a …

The type of vesicular transporter expressed by a neuron is thought to determine its
neurotransmitter phenotype. We show that inactivation of the vesicular inhibitory amino acid …

In addition to photoreceptors and neurons, glial cells (in particular Müller cells) contribute to
the removal and metabolization of neurotransmitters in the neural retina. This review …