Nitric oxide/redox-based signalling as a therapeutic target for penile disorders

AL Burnett, B Musicki, L Jin… - Expert opinion on …, 2006 - Taylor & Francis
Oxidative and/or nitrosative stress is implicated in the pathogeneses of assorted penile
disorders of clinical significance, notably erectile dysfunction, priapism and penile fibrosis. It …

[HTML][HTML] Glycation and protein crosslinking in the diabetes and ageing pathogenesis

M Cárdenas-León, E Díaz-Díaz… - Revista de …, 2009 - medigraphic.com
Long exposition to hyperglycemia is associated with development of vascular diseases in
diabetic patients. Many of these effects are mediated by non-enzymatic glycosylation …

The protective effect of aminoguanidine on erectile function in streptozotocin diabetic rats

MF Usta, TJ Bivalacqua, DY Yang, A Ramanitharan… - The Journal of …, 2003 - Elsevier
PURPOSE: Erectile dysfunction (ED) is frequently associated with diabetes mellitus. We
determined if advanced glycation end products (AGEs) are involved in ED and investigated …

The therapeutic effect of ALT-711 on erectile function in rats treated with high-level AGEs (advanced glycation end products) containing diet

N Gurbuz, R Gurkan, A Ender Caylan… - International Journal of …, 2022 - nature.com
To investigate, if advanced glycation end products (AGEs) are involved in erectile
dysfunction (ED) and also ALT-711, a cross-link breaker of AGEs, has the therapeutic …

Therapeutic effect of combination of alagebrium (ALT-711) and sildenafil on erectile function in diabetic rats

N Gurbuz, G Sagdic, A Sanli, A Ciftcioglu… - International journal of …, 2012 - nature.com
Recently, the relationship between advanced glycation end products (AGEs) and erectile
dysfunction (ED) has been reported. The present study aimed to investigate whether a …

[HTML][HTML] Chronic administration of sildenafil improves erectile function in a rat model of chronic renal failure

N Gurbuz, A Kol, T Ipekci, E Ates… - Asian Journal of …, 2015 - journals.lww.com
The relationship between erectile dysfunction (ED) and chronic renal failure (CRF) has been
reported in several studies. This study aimed to investigate whether the chronic use of …

The protective effect of aminoguanidine on erectile function in diabetic rats is not related to the timing of treatment

MF Usta, TJ Bivalacqua, IT Koksal, B Toptas… - BJU …, 2004 - Wiley Online Library
OBJECTIVE To assess the accumulation of advanced glycation end products (AGEs) in
streptozotocin (STZ)‐induced diabetic rat cavernosal tissue, and to determine whether the …

Protection effect of intracellular melanin from Lachnum YM156 and Haikunshenxi capsule combination on adenine-induced chronic renal failure in mice

S Li, J Li, F Shi, L Yang, M Ye - Medchemcomm, 2017 - pubs.rsc.org
This study aimed to elucidate the therapeutic effects of oral administration of intracellular
melanin from Lachnum YM156 (LIM) on chronic renal failure (CRF) in mice. The cytotoxicity …

The Potential Role of Advanced Glycation End Product and iNOS in Chronic Renal Failure-Related Testicular DysfunctionAn Experimental Study

İT Köksal, MF Usta, G Akkoyunlu, B Toptaş… - American journal of …, 2003 - karger.com
Objectives: To investigate the impact of advanced glycation end products (AGEs) and
inducible nitric oxide synthase (iNOS) in chronic renal failure (CRF)-associated testicular …

[HTML][HTML] Glicación y entrecruzamiento de proteínas en la patogénesis de la diabetes y el envejecimiento

M Cárdenas-León, E Díaz-Díaz… - Revista de …, 2009 - medigraphic.com
Diversos estudios han establecido que la exposición prolongada a la hiperglucemia es el
factor primario asociado con el desarrollo de enfermedades vasculares en pacientes …