Advances in utilizing reverse micelles to investigate membrane proteins

SH Walters, AS Birchfield… - Biochemical Society …, 2024 - portlandpress.com
Reverse micelles (RMs) have emerged as useful tools for the study of membrane associated
proteins. With a nanoscale water core surrounded by surfactant and solubilized in a non …

Electrostatics in computational biophysics and its implications for disease effects

S Sun, P Poudel, E Alexov, L Li - International Journal of Molecular …, 2022 - mdpi.com
This review outlines the role of electrostatics in computational molecular biophysics and its
implication in altering wild-type characteristics of biological macromolecules, and thus the …

Genetically Engineered Liposwitch-Based Nanomaterials

MS Hossain, A Wang, S Anika, Z Zhang… - …, 2024 - ACS Publications
Fusion of intrinsically disordered and globular proteins is a powerful strategy to create
functional nanomaterials. However, the immutable nature of genetic encoding restricts the …

Modifying interprotein interactions for controlling heat-induced protein gelation

S Kumar, D Saha, VK Aswal - Physical Review Materials, 2023 - APS
Globular proteins undergo heat-induced denaturation and eventually gelation at significantly
elevated temperatures. The present study provides pathways to control temperature-driven …

Engineering the kinetic stability of a β-trefoil protein by tuning its topological complexity

DM Anderson, LP Jayanthi, S Gosavi… - Frontiers in Molecular …, 2023 - frontiersin.org
Kinetic stability, defined as the rate of protein unfolding, is central to determining the
functional lifetime of proteins, both in nature and in wide-ranging medical and …

Developing and Applying Computational Methods on Biomolecules

S Sun - 2023 - search.proquest.com
Computational biophysics is an interdisciplinary subject that uses numerical algorithms to
study the physical principles underlying biological phenomena and processes. Electrostatic …

Elucidating the effects of key basic and tryptophan residues on potato plant specific insert structure and function

LKY Cheung - 2024 - open.library.ubc.ca
The plant-specific insert (PSI) is a membrane-active domain of some plant aspartic
proteases that contributes to plant defense against pathogen infection. Despite interest in …