Cardiac arrhythmias are among the leading causes of mortality. They often arise from
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …

Atrial fibrillation (AF) is known to be the most common supraventricular arrhythmia affecting
up to 1% of the general population. Its prevalence exponentially increases with age and …

Background Atrial fibrillation (AF) is a common arrhythmia seen in clinical practice.
Occasionally, no common risk factors are present in patients with this arrhythmia. This …

Atrial fibrillation (AF) is the most common cardiac arrhythmia despite substantial efforts to
understand the pathophysiology of the condition and develop improved treatments …

Variants of SARS-CoV-2 have emerged that are more transmissible than the original virus or
that exhibit some properties of immune escape, or both. The beta (B. 1.351) variant has …

Sudden cardiac death (SCD) is relatively uncommon, yet it is a deadly consequence of
some antipsychotic medications in patients with psychiatric disorders. The widespread …

Cardiac toxicity represents one of the leading causes of drug failure along different stages of
drug development. Multiple very successful pharmaceuticals had to be pulled from the …

Cardiac action potentials are characterized by an initial depolarization followed by a
prolonged depolarization, or plateau phase, before a return to the resting potential. In these …

The IKs channel complex is formed by the co-assembly of Kv7. 1 (KCNQ1), a voltage-gated
potassium channel, with its β-subunit, KCNE1 and the association of numerous accessory …

A substantial proportion of atrial fibrillation (AF) cases cannot be explained by acquired AF
risk factors. Limited guidelines exist that support routine genetic testing. We aim to determine …