Iron addiction with ferroptosis-resistance in asbestos-induced mesothelial carcinogenesis: Toward the era of mesothelioma prevention
S Toyokuni - Free Radical Biology and Medicine, 2019 - Elsevier
Cancer is the primary cause of human mortality in most countries. This tendency has
increased as various medical therapeutics have advanced, which suggests that we cannot …
increased as various medical therapeutics have advanced, which suggests that we cannot …
The origin and future of oxidative stress pathology: From the recognition of carcinogenesis as an iron addiction with ferroptosis‐resistance to non‐thermal plasma …
S Toyokuni - Pathology international, 2016 - Wiley Online Library
Helmut Sies established the concept of oxidative stress in 1985. However, it took some time
to introduce this concept into pathology, where investigators count on formalin‐fixed paraffin …
to introduce this concept into pathology, where investigators count on formalin‐fixed paraffin …
Multi-walled carbon nanotubes trigger lysosome-dependent cell death (pyroptosis) in macrophages but not in neutrophils
Carbon nanotubes (CNTs) have been extensively investigated, and several studies have
shown that multi-walled CNTs can trigger inflammation and fibrosis in animal models …
shown that multi-walled CNTs can trigger inflammation and fibrosis in animal models …
Crosstalk between gut microbiota and lung inflammation in murine toxicity models of respiratory exposure or co-exposure to carbon nanotube particles and cigarette …
Carbon nanotubes (CNTs) are emerging environmental and occupational toxicants known
to induce lung immunotoxicity. While the underlying mechanisms are evolving, it is yet …
to induce lung immunotoxicity. While the underlying mechanisms are evolving, it is yet …
[HTML][HTML] Comparative carcinogenicity study of a thick, straight-type and a thin, tangled-type multi-walled carbon nanotube administered by intra-tracheal instillation in …
DM Saleh, WT Alexander, T Numano… - Particle and fibre …, 2020 - Springer
Background Multi-walled carbon nanotubes can be divided into two general subtypes:
tangled and straight. MWCNT-N (60 nm in diameter) and MWCNT-7 (80–90 nm in diameter) …
tangled and straight. MWCNT-N (60 nm in diameter) and MWCNT-7 (80–90 nm in diameter) …
The impact of multi-walled carbon nanotubes with different amount of metallic impurities on immunometabolic parameters in healthy volunteers
TI Vitkina, VI Yankova, TA Gvozdenko… - Food and Chemical …, 2016 - Elsevier
The impact of two types of multi-walled carbon nanotubes (MWCNTs)(12–14 nm) with
different content of metallic impurities (purified and unpurified nanotubes) on peroxidation …
different content of metallic impurities (purified and unpurified nanotubes) on peroxidation …
[HTML][HTML] Iron links endogenous and exogenous nanoparticles
S Toyokuni, Y Kong, M Katabuchi, Y Maeda… - Archives of Biochemistry …, 2023 - Elsevier
Current progress in biology and medical science is based on the observation at the level of
nanometers via electron microscopy and computation. Of note, the size of most cells in …
nanometers via electron microscopy and computation. Of note, the size of most cells in …
[HTML][HTML] Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats
M Hojo, A Maeno, Y Sakamoto, A Ohnuki… - Particle and Fibre …, 2022 - Springer
Background A mounting number of studies have been documenting the carcinogenic
potential of multiwalled carbon nanotubes (MWCNTs); however, only a few studies have …
potential of multiwalled carbon nanotubes (MWCNTs); however, only a few studies have …
[HTML][HTML] Exposure of Rats to Multi-Walled Carbon Nanotubes: Correlation of Inhalation Exposure to Lung Burden, Bronchoalveolar Lavage Fluid Findings, and Lung …
T Kasai, S Fukushima - Nanomaterials, 2023 - mdpi.com
To evaluate lung toxicity due to inhalation of multi-walled carbon nanotubes (MWCNTs) in
rats, we developed a unique MWCNT aerosol generator based on dry aerosolization using …
rats, we developed a unique MWCNT aerosol generator based on dry aerosolization using …
[HTML][HTML] Nanomaterials and annelid immunity: A comparative survey to reveal the common stress and defense responses of two sentinel species to nanomaterials in …
K Bodó, N Baranzini, R Girardello, B Kokhanyuk… - Biology, 2020 - mdpi.com
Simple Summary Nanotechnology is a dynamically developing field producing large
amounts of nanocompounds that are applied in industry, daily life, and health care. During …
amounts of nanocompounds that are applied in industry, daily life, and health care. During …