Spatiotemporal omics for biology and medicine
The completion of the Human Genome Project has provided a foundational blueprint for
understanding human life. Nonetheless, understanding the intricate mechanisms through …
understanding human life. Nonetheless, understanding the intricate mechanisms through …
Identification of constrained sequence elements across 239 primate genomes
Noncoding DNA is central to our understanding of human gene regulation and complex
diseases,, and measuring the evolutionary sequence constraint can establish the functional …
diseases,, and measuring the evolutionary sequence constraint can establish the functional …
[HTML][HTML] Deciphering the role of structural variation in human evolution: a functional perspective
Advances in sequencing technologies have enabled the comparison of high-quality
genomes of diverse primate species, revealing vast amounts of divergence due to structural …
genomes of diverse primate species, revealing vast amounts of divergence due to structural …
The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression
While CD4+ T cell depletion is key to disease progression in people living with HIV and SIV-
infected macaques, the mechanisms underlying this depletion remain incompletely …
infected macaques, the mechanisms underlying this depletion remain incompletely …
Vocal labeling of others by nonhuman primates
G Oren, A Shapira, R Lifshitz, E Vinepinsky, R Cohen… - Science, 2024 - science.org
Humans, dolphins, and elephants are the only known species that vocally label their
conspecifics. It remains unclear whether nonhuman primates share this ability. We recorded …
conspecifics. It remains unclear whether nonhuman primates share this ability. We recorded …
A hybrid genome assembly of the endangered aye-aye (Daubentonia madagascariensis)
CJ Versoza, SP Pfeifer - G3: Genes, Genomes, Genetics, 2024 - academic.oup.com
The aye-aye (Daubentonia madagascariensis) is the only extant member of the
Daubentoniidae primate family. Although several reference genomes exist for this …
Daubentoniidae primate family. Although several reference genomes exist for this …
Complete sequencing of ape genomes
We present haplotype-resolved reference genomes and comparative analyses of six ape
species, namely: chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan …
species, namely: chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan …
[PDF][PDF] Integrative omics reveals rapidly evolving regulatory sequences driving primate brain evolution
XL Zhuang, JJ Zhang, Y Shao, Y Ye… - Molecular Biology …, 2023 - academic.oup.com
Although the continual expansion of the brain during primate evolution accounts for our
enhanced cognitive capabilities, the drivers of brain evolution have scarcely been explored …
enhanced cognitive capabilities, the drivers of brain evolution have scarcely been explored …
Discovering fragile clades and causal sequences in phylogenomics by evolutionary sparse learning
Phylogenomic analyses of long sequences, consisting of many genes and genomic
segments, reconstruct organismal relationships with high statistical confidence. But, inferred …
segments, reconstruct organismal relationships with high statistical confidence. But, inferred …
Complex evolutionary history with extensive ancestral gene flow in an African primate radiation
Understanding the drivers of speciation is fundamental in evolutionary biology, and recent
studies highlight hybridization as an important evolutionary force. Using whole-genome …
studies highlight hybridization as an important evolutionary force. Using whole-genome …