Intensive care unit–acquired weakness: clinical phenotypes and molecular mechanisms

J Batt, CC Dos Santos, JI Cameron… - American journal of …, 2013 - atsjournals.org
Intensive care unit–acquired weakness (ICUAW) begins within hours of mechanical
ventilation and may not be completely reversible over time. It represents a major functional …

The link of organophosphorus pesticides with neurodegenerative and neurodevelopmental diseases based on evidence and mechanisms

S Mostafalou, M Abdollahi - Toxicology, 2018 - Elsevier
Organophosphorus (OP) compounds have been known as the most widely used pesticides
during the past half century and there have been a huge body of literature regarding their …

Acute and long‐term consequences of exposure to organophosphate nerve agents in humans

TH Figueiredo, JP Apland, MFM Braga, AM Marini - Epilepsia, 2018 - Wiley Online Library
Nerve agents are organophosphate (OP) compounds and among the most powerful poisons
known to man. A terrorist attack on civilian or military populations causing mass casualties is …

Neuronal AChE splice variants and their non‐hydrolytic functions: redefining a target of AChE inhibitors?

M Zimmermann - British journal of pharmacology, 2013 - Wiley Online Library
AChE enzymatic inhibition is a core focus of pharmacological intervention in A lzheimer's
disease (AD). Yet, AChE has also been ascribed non‐hydrolytic functions, which seem …

ICU-acquired weakness: mechanisms of disability

CC Dos Santos, J Batt - Current opinion in critical care, 2012 - journals.lww.com
Variable contributions of structural and functional changes likely contribute to both early and
late myopathy and neuropathy, although the specifics of the temporality of both processes …

Electrochemical biosensors based on acetylcholinesterase and butyrylcholinesterase. A review

M Pohanka - International Journal of Electrochemical Science, 2016 - Elsevier
Two cholinesterases are known: acetylcholinesterase (AChE) and butyrylcholinesterase
(BChE). The both enzymes are presented in the body under physiological conditions and …

Stress‐induced alternative splicing modulations in brain and periphery: acetylcholinesterase as a case study

I Shaked, G Zimmerman, H Soreq - Annals of the New York …, 2008 - Wiley Online Library
Mammalian stress responses present a case study for investigating alternative splicing
reactions in general, and changes in acetylcholinesterase (AChE) gene expression in …

[HTML][HTML] Anti-glioma effect of pseudosynanceia melanostigma venom on isolated mitochondria from glioblastoma cells

M Ramezani, F Samiei, J Pourahmad - Asian Pacific Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Glioblastoma is the most common primary malignant tumor of the central
nervous system that occurs in the spinal cord or brain. Pseudosynanceia Melanostigma is a …

[图书][B] Cholinergic pesticides

C Falugi, C Guida, H Thielecke, MG Aluigi… - 2011 - researchgate.net
The use of protection plant products for the control of pests in agriculture is very ancient:
thousands of years ago, Greek and Chinese people knew the insecticide properties of sulfur …

Characterization of Crystals Isolated from the Caesalpinia sappan Seeds: A Comparative In Silico Analysis on Bioactivity of Sappan Diterpenoids

H Ravi Kumar, S Nagaraju, K Krishnamurthy… - … Product Experiments in …, 2022 - Springer
Objective. Caesalpinia sappan is a genus of plants belonging to the family Fabaceae found
in East and Southeast Asia. Pharmacologically, species of this sort display anti …