The pulmonary vasculature has been frequently overlooked in acute and chronic lung
diseases, such as acute respiratory distress syndrome (ARDS), pulmonary fibrosis (PF), and …

Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality in the
adult population worldwide and represent a severe economic burden and public health …

Cardiovascular diseases (CVDs), especially those involving a systemic inflammatory
process such as atherosclerosis, remain the leading cause of morbidity and mortality in …

Senescent cells persist and continuously secrete proinflammatory and tissue-remodeling
molecules that poison surrounding cells, leading to various age-related diseases, including …

Exosomes from senescence cells play pivotal roles in endothelium dysfunction. We
investigated the exosomal angiogenic cargo of endothelial cells (ECs) in a model of …

After an ischemic injury, the heart undergoes a complex process of structural and functional
remodeling that involves several steps, including inflammatory and fibrotic responses. In this …

Aging is one of the hottest topics in biomedical research. Advances in research and
medicine have helped to preserve human health, leading to an extension of life expectancy …

Hypoxia-inducible factors (HIFs) are transcription factors that reprogram the transcriptome
for cells to survive hypoxic insults and oxidative stress. They are important during embryonic …

Cardiovascular aging presents a formidable challenge, as the aging process can lead to
reduced cardiac function and heightened susceptibility to cardiovascular diseases …

The pathophysiology of atrial fibrillation (AF) may involve atrial fibrosis/remodeling and
dysfunctional endothelial activities. Despite the currently available treatment approaches …