Intercellular pathways of cancer treatment-related cardiotoxicity and their therapeutic implications: the paradigm of radiotherapy
Advances in cancer therapeutics have improved patient survival rates. However, cancer
survivors may suffer from adverse events either at the time of therapy or later in life …
survivors may suffer from adverse events either at the time of therapy or later in life …
Cardiac ageing: from hallmarks to therapeutic opportunities
Cardiac ageing is an intricate and multifaceted process with considerable impact on public
health, especially given the global demographic shift towards aged populations. This review …
health, especially given the global demographic shift towards aged populations. This review …
Pharmacokinetics and cardioprotective efficacy of intravenous miR‐125b* microRNA mimic in a mouse model of acute myocardial infarction
Background and purpose MicroRNA (miRNA) therapy is a promising approach to induce
cardioprotection. We have previously identified cardiac microRNA‐125b*(microRNA‐125b …
cardioprotection. We have previously identified cardiac microRNA‐125b*(microRNA‐125b …
[HTML][HTML] Activins and Inhibins in Cardiovascular Pathophysiology
W Tang, Z Gu, J Guo, M Lin, H Tao, D Jia, P Jia - Biomolecules, 2024 - mdpi.com
Activins and inhibins, members of the transforming growth factor β (TGFβ) superfamily, were
initially recognized for their opposing effects on the secretion of follicle-stimulating hormone …
initially recognized for their opposing effects on the secretion of follicle-stimulating hormone …
Prognostic Significance of Proteomics‐Discovered Circulating Inflammatory Biomarkers in Patients With Pulmonary Arterial Hypertension
T Yokokawa, O Boucherat, S Martineau… - Journal of the …, 2024 - Am Heart Assoc
Background Pulmonary arterial hypertension (PAH) ultimately leads to right ventricular
failure and premature death. The identification of circulating biomarkers with prognostic …
failure and premature death. The identification of circulating biomarkers with prognostic …
Immune Markers, Blood Pressure Severity, and Cardiac Remodeling 1 to 2 Years After Hypertensive Disorders of Pregnancy
A Koczo, A Hauspurg, ME Countouris… - Journal of the …, 2023 - Am Heart Assoc
Background Cardiovascular dysfunction and hypertension can persist postpartum following
hypertensive disorders of pregnancy (HDPs). This study hypothesized that activin A …
hypertensive disorders of pregnancy (HDPs). This study hypothesized that activin A …
Molecular remodeling in comorbidities associated with heart failure: a current update
S Appunni, M Rubens, V Ramamoorthy… - Molecular biology …, 2024 - Springer
Recent advances in genomics and proteomics have helped in understanding the molecular
mechanisms and pathways of comorbidities and heart failure. In this narrative review, we …
mechanisms and pathways of comorbidities and heart failure. In this narrative review, we …
Defining the cardiac fibroblast secretome in the healthy and infarcted mouse heart
J Bahr, G Poschmann, A Jungmann, M Busch, Z Ding… - bioRxiv, 2024 - biorxiv.org
Cardiac fibroblasts (CF) are key players after myocardial infarction (MI), but their signaling is
only incompletely understood. Here we report a first secretome atlas of CF in control (cCF) …
only incompletely understood. Here we report a first secretome atlas of CF in control (cCF) …
[PDF][PDF] Quantitative secretome analysis of cardiac fibroblasts in the control heart and after myocardial infarction
J Bahr - 2024 - docserv.uni-duesseldorf.de
Myocardial infarction (MI) is still the leading cause of death worldwide. Especially cardiac
fibrosis, which mediates myocardial stiffness and impairs cardiac function resulting in heart …
fibrosis, which mediates myocardial stiffness and impairs cardiac function resulting in heart …