[HTML][HTML] Lipid metabolism, apoptosis and cancer therapy
C Huang, C Freter - International journal of molecular sciences, 2015 - mdpi.com
Lipid metabolism is regulated by multiple signaling pathways, and generates a variety of
bioactive lipid molecules. These bioactive lipid molecules known as signaling molecules …
bioactive lipid molecules. These bioactive lipid molecules known as signaling molecules …
[HTML][HTML] Influence of cholesterol on cancer progression and therapy
SS Mayengbam, A Singh, AD Pillai, MK Bhat - Translational oncology, 2021 - Elsevier
Cholesterol is a fundamental molecule necessary for the maintenance of cell structure and is
vital to various normal biological functions. It is a key factor in lifestyle-related diseases …
vital to various normal biological functions. It is a key factor in lifestyle-related diseases …
[HTML][HTML] Peptostreptococcus anaerobius induces intracellular cholesterol biosynthesis in colon cells to induce proliferation and causes dysplasia in mice
Background & Aims Stool samples from patients with colorectal cancer (CRC) have a higher
abundance of Peptostreptococcus anaerobius than stool from individuals without CRC …
abundance of Peptostreptococcus anaerobius than stool from individuals without CRC …
[HTML][HTML] The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics
PMR Cruz, H Mo, WJ McConathy, N Sabnis… - Frontiers in …, 2013 - frontiersin.org
While the unique metabolic activities of malignant tissues as potential targets for cancer
therapeutics has been the subject of several recent reviews, the role of cholesterol …
therapeutics has been the subject of several recent reviews, the role of cholesterol …
[HTML][HTML] Cholesterol metabolic reprogramming in cancer and its pharmacological modulation as therapeutic strategy
I Giacomini, F Gianfanti, MA Desbats, G Orso… - Frontiers in …, 2021 - frontiersin.org
Cholesterol is a ubiquitous sterol with many biological functions, which are crucial for proper
cellular signaling and physiology. Indeed, cholesterol is essential in maintaining membrane …
cellular signaling and physiology. Indeed, cholesterol is essential in maintaining membrane …
[HTML][HTML] Advances in management of bladder cancer—the role of photodynamic therapy
T Kubrak, M Karakuła, M Czop, A Kawczyk-Krupka… - Molecules, 2022 - mdpi.com
Photodynamic therapy (PDT) is a non-invasive and modern form of therapy. It is used in the
treatment of non-oncological diseases and more and more often in the treatment of various …
treatment of non-oncological diseases and more and more often in the treatment of various …
Lipoproteins and lipoprotein mimetics for imaging and drug delivery
Lipoproteins are a set of natural nanoparticles whose main role is the transport of fats within
the body. While much work has been done to develop synthetic nanocarriers to deliver …
the body. While much work has been done to develop synthetic nanocarriers to deliver …
[HTML][HTML] Targeting the SR-B1 receptor as a gateway for cancer therapy and imaging
LK Mooberry, NA Sabnis, M Panchoo… - Frontiers in …, 2016 - frontiersin.org
Malignant tumors display remarkable heterogeneity to the extent that even at the same
tissue site different types of cells with varying genetic background may be found. In contrast …
tissue site different types of cells with varying genetic background may be found. In contrast …
[HTML][HTML] Role of de novo cholesterol synthesis enzymes in cancer
J Yang, L Wang, R Jia - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Despite extensive research in the cancer field, cancer remains one of the most prevalent
diseases. There is an urgent need to identify specific targets that are safe and effective for …
diseases. There is an urgent need to identify specific targets that are safe and effective for …
[HTML][HTML] Unraveling the anticancer potential of statins: Mechanisms and clinical significance
MY Zaky, C Fan, H Zhang, XF Sun - Cancers, 2023 - mdpi.com
Simple Summary Statins are crucial for managing lipid disorders by inhibiting HMG-CoA
reductase, reducing cholesterol levels, and lowering cardiovascular disease risk. Beyond …
reductase, reducing cholesterol levels, and lowering cardiovascular disease risk. Beyond …