Aptamers Targeting the PD-1/PD-L1 Axis: A Perspective

P Bertrand - Journal of Medicinal Chemistry, 2023 - ACS Publications
Aptamers have emerged in recent years as alternatives to antibodies or small molecules to
interfere with the immune check points by blocking the PD-1/PD-L1 interactions and …

DNA nanoprobes for detection and imaging of glycoproteins

C Zhang, Z Zhou, S Fu, C Yu, M Irfan, X Su - Nano Today, 2023 - Elsevier
Aberrant glycoforms of glycoproteins, resulting from changes in their post-translational
modification patterns, are often linked to the onset of various disorders. Early detection and …

Recent Advances in Protein‐Specific Glycan Imaging and Editing

X Zheng, B He, L Meng, R Xie - Chembiochem, 2023 - Wiley Online Library
Glycosylation in live cell and animal modulate a constellation of biological functions. The
advent of Chemical Biology has revolutionized the analysis and tailoring of glycans, by …

Proximity-driven bioorthogonal reactions via DNA circuits enable the accurate aptasensing of non-nucleic acid targets

SJ Zhao, H Guo, Z Wu, JH Jiang - Chemical Communications, 2022 - pubs.rsc.org
Proximity-driven bioorthogonal reactions via DNA circuits enable the accurate aptasensing
of non-nucleic acid targets - Chemical Communications (RSC Publishing) DOI:10.1039/D2CC05628C …

A multiparametric fluorescent visualization approach for detecting drug resistance in living cancer cells

Z Zhou, Y Wang, Z Shao, G Zhang, H Jiang, Y Tang… - Talanta, 2023 - Elsevier
Drug resistance is a worldwide health care crisis which impedes disease treatment and
increases financial burden, especially for its multifactorial nature and high complexity …

Bioorthogonal Probes for Analyzing Non‐Enzymatic Post‐Translational Modifications

Z Shao, Y Zhu, J Li - ChemBioChem, 2023 - Wiley Online Library
Non‐enzymatic post‐translational modifications (nPTMs) have been proposed as indicators
of cellular stresses and diseases. Unfortunately, direct assessment of nPTMs in native …

Cell Membrane Functionalization via Nucleic Acid Tools for Visualization and Regulation of Cellular Receptors

S Chen, J Li, H Yang - … for Cell Research: From Bioanalysis to …, 2024 - Wiley Online Library
Among nucleic acid‐based cell membrane functionalization strategies, target recognition is
a common route to attach DNA probes on receptors via modifying DNA with receptor …