Recent advances in biosensors based on enzyme inhibition

A Amine, F Arduini, D Moscone, G Palleschi - Biosensors and …, 2016 - Elsevier
Enzyme inhibitors like drugs and pollutants are closely correlated to human and
environmental health, thus their monitoring is of paramount importance in analytical …

Recent advances in electrochemical biosensors based on enzyme inhibition for clinical and pharmaceutical applications

L El Harrad, I Bourais, H Mohammadi, A Amine - Sensors, 2018 - mdpi.com
A large number of enzyme inhibitors are used as drugs to treat several diseases such as
gout, diabetes, AIDS, depression, Parkinson's and Alzheimer's diseases. Electrochemical …

Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation

S Kumar - Expert opinion on drug metabolism & toxicology, 2010 - Taylor & Francis
Importance of the field: Cytochrome P450 enzymes comprise a superfamily of heme
monooxygenases that are of considerable interest for the: i) synthesis of novel drugs and …

A zinc oxide nanorods/molybdenum disulfide nanosheets hybrid as a sensitive and reusable electrochemical sensor for determination of anti-retroviral agent indinavir

M Mehmandoust, F Karimi, N Erk - Chemosphere, 2022 - Elsevier
This work aims to develop an electrochemical sensor for the reusable and selective
detection of trace levels of indinavir (IDV) as an anti-retroviral drug by using zinc oxide nano …

Electrochemical detection of anti-breast-cancer agents in human serum by cytochrome P450-coated carbon nanotubes

C Baj-Rossi, G De Micheli, S Carrara - Sensors, 2012 - mdpi.com
We report on the electrochemical detection of anti-cancer drugs in human serum with
sensitivity values in the range of 8–925 nA/μM. Multi-walled carbon nanotubes were …

Current approaches for investigating and predicting cytochrome P450 3A4-ligand interactions

IF Sevrioukova, TL Poulos - Monooxygenase, peroxidase and …, 2015 - Springer
Abstract Cytochrome P450 3A4 (CYP3A4) is the major and most important drug-
metabolizing enzyme in humans that oxidizes and clears over a half of all administered …

Electroanalytical methods for determination of antiviral drugs in pharmaceutical formulation and biological fluids: A review

Z AYDOĞMUŞ, A Asfoor - Chinese Journal of Analytical Chemistry, 2022 - Elsevier
Viruses can infect all kinds of life forms, from humans, animals and plants to
microorganisms, including bacteria and archaea, and can cause serious illness, including a …

Developing biosensors in developing countries: South Africa as a case study

R Fogel, J Limson - Biosensors, 2016 - mdpi.com
A mini-review of the reported biosensor research occurring in South Africa evidences a
strong emphasis on electrochemical sensor research, guided by the opportunities this …

[图书][B] Industrial biocatalysis

P Grunwald - 2014 - books.google.com
Biocatalysis has become an essential tool in the chemical industry and is the core of
industrial biotechnology, also known as white biotechnology, making use of biocatalysts in …

A new standardized electrochemical array for drug metabolic profiling with human cytochromes P450

A Fantuzzi, LH Mak, E Capria, V Dodhia… - Analytical …, 2011 - ACS Publications
Over the past two decades, a wealth of information on the human cytochrome P450
enzymes and their role in drug metabolism both in vitro and in vivo has been gathered. Our …