Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets
T Loganathan, GP Doss C - Functional & Integrative Genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …
the origin, course of action and treatment of any disease state is essential. A microscopic …
MicroRNA as biomarkers and diagnostics
J Wang, J Chen, S Sen - Journal of cellular physiology, 2016 - Wiley Online Library
MicroRNAs (miRNAs) are a group of small non‐coding RNAs that are involved in regulating
a range of developmental and physiological processes; their dysregulation has been …
a range of developmental and physiological processes; their dysregulation has been …
miRTarBase 2020: updates to the experimentally validated microRNA–target interaction database
MicroRNAs (miRNAs) are small non-coding RNAs (typically consisting of 18–25
nucleotides) that negatively control expression of target genes at the post-transcriptional …
nucleotides) that negatively control expression of target genes at the post-transcriptional …
[HTML][HTML] Muscle-specific microRNAs in skeletal muscle development
M Horak, J Novak, J Bienertova-Vasku - Developmental biology, 2016 - Elsevier
Proper muscle function constitutes a precondition for good heath and an active lifestyle
during an individual's lifespan and any deviations from normal skeletal muscle development …
during an individual's lifespan and any deviations from normal skeletal muscle development …
[HTML][HTML] A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA
M Cesana, D Cacchiarelli, I Legnini, T Santini… - Cell, 2011 - cell.com
Recently, a new regulatory circuitry has been identified in which RNAs can crosstalk with
each other by competing for shared microRNAs. Such competing endogenous RNAs …
each other by competing for shared microRNAs. Such competing endogenous RNAs …
[HTML][HTML] miRWalk–database: prediction of possible miRNA binding sites by “walking” the genes of three genomes
H Dweep, C Sticht, P Pandey, N Gretz - Journal of biomedical informatics, 2011 - Elsevier
MicroRNAs are small, non-coding RNA molecules that can complementarily bind to the
mRNA 3′-UTR region to regulate the gene expression by transcriptional repression or …
mRNA 3′-UTR region to regulate the gene expression by transcriptional repression or …
[HTML][HTML] The role of microRNAs in human diseases
AM Ardekani, MM Naeini - Avicenna journal of medical …, 2010 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are short RNA molecules which bind to target mRNAs, resulting in
translational repression and gene silencing and are found in all eukaryotic cells …
translational repression and gene silencing and are found in all eukaryotic cells …
miRTarBase update 2022: an informative resource for experimentally validated miRNA–target interactions
MicroRNAs (miRNAs) are noncoding RNAs with 18–26 nucleotides; they pair with target
mRNAs to regulate gene expression and produce significant changes in various …
mRNAs to regulate gene expression and produce significant changes in various …
LNA-mediated microRNA silencing in non-human primates
Abstract microRNAs (miRNAs) are small regulatory RNAs that are important in development
and disease,, and therefore represent a potential new class of targets for therapeutic …
and disease,, and therefore represent a potential new class of targets for therapeutic …
microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7
JF Chen, Y Tao, J Li, Z Deng, Z Yan, X Xiao… - Journal of Cell …, 2010 - rupress.org
Skeletal muscle satellite cells are adult stem cells responsible for postnatal skeletal muscle
growth and regeneration. Paired-box transcription factor Pax7 plays a central role in satellite …
growth and regeneration. Paired-box transcription factor Pax7 plays a central role in satellite …