Cell death and ischemia-reperfusion injury in lung transplantation

M Capuzzimati, O Hough, M Liu - The Journal of Heart and Lung …, 2022 - Elsevier
Lung transplantation is the most effective therapy for patients with end-stage lung disease.
However, concern of donor lung damage and ischemia-reperfusion induced lung injury …

Cellular recovery after prolonged warm ischaemia of the whole body

D Andrijevic, Z Vrselja, T Lysyy, S Zhang, M Skarica… - Nature, 2022 - nature.com
After cessation of blood flow or similar ischaemic exposures, deleterious molecular
cascades commence in mammalian cells, eventually leading to their death,. Yet with …

[HTML][HTML] Ischemia–Reperfusion Injury in Kidney Transplantation: Mechanisms and Potential Therapeutic Targets

F Lasorsa, M Rutigliano, M Milella, A d'Amati… - International Journal of …, 2024 - mdpi.com
Kidney transplantation offers a longer life expectancy and a better quality of life than dialysis
to patients with end-stage kidney disease. Ischemia–reperfusion injury (IRI) is thought to be …

Klf6 aggravates myocardial ischemia/reperfusion injury by activating Acsl4‐mediated ferroptosis

ML Qiu, W Yan, MM Liu - The Kaohsiung Journal of Medical …, 2023 - Wiley Online Library
Ferroptosis is closely related to myocardial ischemia/reperfusion (I/R) damage. Kruppel‐like
factor 6 (Klf6) can aggravate renal I/R injury. We aimed to elucidate the role of Klf6 in …

LncRNA MALAT1 Promoted Neuronal Necroptosis in Cerebral Ischemia-reperfusion Mice by Stabilizing HSP90

S Huang, D Hou, L Zhang, C Pei, J Liang, J Li… - Neurochemical …, 2023 - Springer
The objective of this research was to investigate the role of lncRNA MALAT1 and HSP90 in
the regulation of neuronal necroptosis in mice with cerebral ischemia-reperfusion (CIR). We …

[HTML][HTML] IKK1 aggravates ischemia–reperfusion kidney injury by promoting the differentiation of effector T cells

N Song, Y Xu, HJ Paust, U Panzer… - Cellular and Molecular …, 2023 - Springer
Ischemia–reperfusion injury (IRI) is one of the major causes of acute kidney injury (AKI), and
experimental work has revealed detailed insight into the inflammatory response in the …

Advanced MRI to assess hippocampal injury after incomplete cerebral ischemia‐reperfusion in rats

L Fu, LM Zhang, LN Guan, YC Song… - Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose The purpose of this study was to evaluate advanced MRI
findings in the bilateral hippocampus CA1 region of rats with hemorrhagic shock reperfusion …

[HTML][HTML] Edgeworthia gardneri (Wall.) Meisn. Ethanolic Extract Attenuates Endothelial Activation and Alleviates Cardiac Ischemia-Reperfusion Injury

X Lang, C Zhong, L Su, M Qin, Y Xie, D Shan, Y Cui… - Molecules, 2024 - mdpi.com
Endothelial pro-inflammatory activation is pivotal in cardiac ischemia–reperfusion (I/R) injury
pathophysiology. The dried flower bud of Edgeworthia gardneri (Wall.) Meisn.(EG) is a …

Role of the immune system in liver transplantation and its implications for therapeutic interventions

G Chen, X Hu, Y Huang, X Xiang, S Pan, R Chen… - MedComm, 2023 - Wiley Online Library
Liver transplantation (LT) stands as the gold standard for treating end‐stage liver disease
and hepatocellular carcinoma, yet postoperative complications continue to impact survival …

[HTML][HTML] Transcriptomic Landscape of Circulating Extracellular Vesicles in Heart Transplant Ischemia–Reperfusion

SJ Joo, K Dhaygude, S Westerberg, R Krebs, M Puhka… - Genes, 2023 - mdpi.com
Ischemia–reperfusion injury (IRI) is an inevitable event during heart transplantation, which is
known to exacerbate damage to the allograft. However, the precise mechanisms underlying …