Metabolomics as a valid analytical technique in environmental exposure research: application and progress

S Wei, Y Wei, Y Gong, Y Chen, J Cui, L Li, H Yan, Y Yu… - Metabolomics, 2022 - Springer
Background In recent years, studies have shown that exposure to environmental pollutants
(eg, radiation, heavy metal substances, air pollutants, organic pollutants) is a leading cause …

Progress in Mechanisms, Pathways and Cohort Studies About the Effects of PM2.5 Exposure on the Central Nervous System

M Ye, J Yang, J Li, Y Wang, W Chen, L Zhu… - Reviews of …, 2023 - Springer
An increasing number of studies have shown that particulate matter (PM) exposure can
produce damaging effects on respiratory and cardiovascular systems, however, whether PM …

[HTML][HTML] Perturbation of arachidonic acid and glycerolipid metabolism promoted particulate matter-induced inflammatory responses in human bronchial epithelial cells

J Wang, Y Zeng, J Song, M Zhu, G Zhu, H Cai… - Ecotoxicology and …, 2023 - Elsevier
Particulate matter (PM) has become the main risk factor for public health, being linked with
an increased risk of respiratory diseases. However, the potential mechanisms underlying …

[HTML][HTML] Crosstalk between TM4SF5 and GLUT8 regulates fructose metabolism in hepatic steatosis

H Lee, E Kim, EA Shin, JC Shon, H Sun, JE Kim… - Molecular …, 2022 - Elsevier
Objective Transmembrane 4 L six family member 5 (TM4SF5) is likely involved in non-
alcoholic steatohepatitis, although its roles and cross-talks with glucose/fructose transporters …

Chronic Real-Ambient PM2.5 Exposure Exacerbates Cardiovascular Risk via Amplifying Liver Injury in Mice Fed with a High-Fat and High-Cholesterol Diet

Y Chen, HL Ngan, Y Song, Z Qi, L Zhao… - Environment & …, 2024 - ACS Publications
Epidemiology has associated fine particulate matter (PM2. 5) exposure with an increased
cardiovascular risk. However, the underlying mechanism, particularly from the liver …

[HTML][HTML] Unraveling the mechanisms of benzo [a] pyrene degradation by Pigmentiphaga kullae strain KIT-003 using a multi-omics approach

Y Jeon, YS Kwon, YJ Noh, SM Lee, J Song… - Ecotoxicology and …, 2024 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs), notably benzo [a] pyrene (BaP), are
environmental contaminants with multiple adverse ecological implications. Numerous …

Association of lower plasma citric acid with prolonged cough: the Nagahama study

S Terada, H Matsumoto, K Nishi, M Kogo, N Nomura… - Scientific Reports, 2023 - nature.com
Little is known about the association of prolonged cough, a common and troublesome
symptom, with metabolic pathways. We aimed to clarify this association using data from the …

Metabolic dysregulations underlying the pulmonary toxicity of atmospheric fine particulate matter: focus on energy-producing pathways and lipid metabolism

TD Silva, C Alves, H Oliveira, IF Duarte - Air Quality, Atmosphere & Health, 2022 - Springer
Exposure to atmospheric fine particulate matter (PM2. 5) is currently recognized as a leading
cause and/or a serious aggravating factor of several respiratory diseases, such as chronic …

Comprehensive Untargeted Lipidomic Profiling of Third Generation Lentiviral Vectors and Packaging Cells

J Roberts, E Godbout, J Menard, CN Boddy… - Molecular …, 2024 - pubs.rsc.org
Lentiviral Vectors (LV) are emerging tools for genetic therapies and novel cancer treatments.
While effective, LV-based therapies have extremely large costs associated with their …

[HTML][HTML] Promotion of myofibroblast differentiation through repeated treatment of fibroblasts to low concentrations of PM2. 5

NA Craig, AM Scruggs, JP Berens, F Deng… - Environmental …, 2024 - Elsevier
Exposure to particulate matter≤ 2.5 µm (PM 2.5) is a risk factor for many lung diseases.
Although the toxicologic effects of PM 2.5 on airway epithelium are well-described, the …