Emerging droplet microfluidics

L Shang, Y Cheng, Y Zhao - Chemical reviews, 2017 - ACS Publications
Droplet microfluidics generates and manipulates discrete droplets through immiscible
multiphase flows inside microchannels. Due to its remarkable advantages, droplet …

Microfluidic fabrication of microparticles for biomedical applications

W Li, L Zhang, X Ge, B Xu, W Zhang, L Qu… - Chemical Society …, 2018 - pubs.rsc.org
Droplet microfluidics offers exquisite control over the flows of multiple fluids in microscale,
enabling fabrication of advanced microparticles with precisely tunable structures and …

Single-cell barcoding and sequencing using droplet microfluidics

R Zilionis, J Nainys, A Veres, V Savova, D Zemmour… - Nature protocols, 2017 - nature.com
Single-cell RNA sequencing has recently emerged as a powerful tool for mapping cellular
heterogeneity in diseased and healthy tissues, yet high-throughput methods are needed for …

Recent advances in droplet microfluidics

Y Ding, PD Howes, AJ deMello - Analytical chemistry, 2019 - ACS Publications
Prominent within this technology set are droplet-based microfluidic systems, 3 in which
passive microfluidic structures are used to rapidly generate and manipulate subnanoliter …

Cancer biomarker detection: recent achievements and challenges

L Wu, X Qu - Chemical Society Reviews, 2015 - pubs.rsc.org
The early detection of cancer can significantly reduce cancer mortality and saves lives. Thus,
a great deal of effort has been devoted to the exploration of new technologies to detect early …

Single-cell genome sequencing at ultra-high-throughput with microfluidic droplet barcoding

F Lan, B Demaree, N Ahmed, AR Abate - Nature biotechnology, 2017 - nature.com
The application of single-cell genome sequencing to large cell populations has been
hindered by technical challenges in isolating single cells during genome preparation. Here …

Trends in droplet microfluidics: From droplet generation to biomedical applications

Z Chen, S Kheiri, EWK Young, E Kumacheva - Langmuir, 2022 - ACS Publications
Over the past decade, droplet microfluidics has attracted growing interest in biology,
medicine, and engineering. In this feature article, we review the advances in droplet …

Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology

M He, J Crow, M Roth, Y Zeng, AK Godwin - Lab on a Chip, 2014 - pubs.rsc.org
Developing blood-based tests is appealing for non-invasive disease diagnosis, especially
when biopsy is difficult, costly, and sometimes not even an option. Tumor-derived exosomes …

Development and future of droplet microfluidics

L Nan, H Zhang, DA Weitz, HC Shum - Lab on a Chip, 2024 - pubs.rsc.org
Over the past two decades, advances in droplet-based microfluidics have facilitated new
approaches to process and analyze samples with unprecedented levels of precision and …

Droplet microfluidics—A tool for single‐cell analysis

HN Joensson… - Angewandte Chemie …, 2012 - Wiley Online Library
Droplet microfluidics allows the isolation of single cells and reagents in monodisperse
picoliter liquid capsules and manipulations at a throughput of thousands of droplets per …