Progressive multifocal leukoencephalopathy (PML) is a devastating CNS infection caused
by JC virus (JCV), a polyomavirus that commonly establishes persistent, asymptomatic …

Viruses are the cause of approximately 15% of all human cancers. Both RNA and DNA
human tumor viruses have been identified, with Merkel cell polyomavirus being the most …

Viral egress and transmission have long been described to take place through single free
virus particles. However, viruses can also shed into the environment and transmit as …

Viruses are ubiquitous, essential components of any ecosystem, and of multicellular
organism holobionts. Numerous viruses cause acute infection, killing the host or being …

Viruses have been infecting their host cells since the dawn of life, and this extremely long-
term coevolution gave rise to some surprising consequences for the entire tree of life. It is …

The polyomavirus family currently includes thirteen human polyomavirus (HPyV) species. In
immunocompromised and elderly persons HPyVs are known to cause disease, such as …

Bladder cancer (BC) is a complex disease affecting the urinary system and is regulated by
several carcinogenic factors. Viral infection is one such factor that has attracted extensive …

BK polyomavirus (BKV) is an important cause of graft loss in renal transplant recipients that
continues to pose a significant challenge to clinicians due to its frequently unpredictable …

Simple Summary By studying the cancer-inducing ability of polyomaviruses, several
milestones in cancer research crucially contributing to our current understanding of, eg, the …

Circular RNAs (circRNAs) are a conserved class of RNAs with diverse functions, including
serving as messenger RNAs that are translated into peptides. Here we describe circular …