Procedural treatments for knee osteoarthritis: a review of current injectable therapies

LM Billesberger, KM Fisher, YJ Qadri… - Pain Research and …, 2020 - Wiley Online Library
Knee osteoarthritis is a common painful degenerative condition affecting the aging
Canadian population. In addition to pain and disability, osteoarthritis is associated with …

Dextrose prolotherapy: a narrative review of basic science, clinical research, and best treatment recommendations

KD Reeves, RWS Sit, DP Rabago - Physical Medicine and …, 2016 - pmr.theclinics.com
Methods A search of electronic databases was performed by the University of Kansas library
staff, including Medline, Web of Science, and ClinicalTrials. gov, from 1980 to 2016, without …

Prolotherapy for osteoarthritis and tendinopathy: a descriptive review

D Rabago, B Nourani - Current rheumatology reports, 2017 - Springer
Abstract Purpose of Review Osteoarthritis and overuse tendinopathy are common chronic
conditions of high societal and patient burden. The precise etiology of pain and disability in …

Dextrose prolotherapy in knee osteoarthritis: A systematic review and meta-analysis

TC Wee, EJR Neo, YL Tan - Journal of Clinical Orthopaedics and Trauma, 2021 - Elsevier
Objective To summarize the evidence for dextrose prolotherapy in knee osteoarthritis. Data
sources The authors searched PubMed and Embase from inception to September 2020. All …

Current and novel therapeutics for articular cartilage repair and regeneration

B Cong, T Sun, Y Zhao, M Chen - Therapeutics and Clinical Risk …, 2023 - Taylor & Francis
Articular cartilage repair is a sophisticated process that has is being recently investigated.
There are several different approaches that are currently reported to promote cartilage …

Efficacy of intra-articular hypertonic dextrose (prolotherapy) for knee osteoarthritis: a randomized controlled trial

RWS Sit, RWK Wu, D Rabago… - The Annals of Family …, 2020 - Annals Family Med
PURPOSE To test the efficacy of intra-articular hypertonic dextrose prolotherapy (DPT) vs
normal saline (NS) injection for knee osteoarthritis (KOA). METHODS A single-center …

A role for substance P and acid-sensing ion channel 1a in prolotherapy with dextrose-mediated analgesia in a mouse model of chronic muscle pain

DS Han, CH Lee, YD Shieh, CT Chang, MH Li, YC Chu… - Pain, 2022 - journals.lww.com
Prolotherapy is widely used in pain control and tissue repair in pain medicine. The classical
mode is injection with hypertonic dextrose in muscle or perimysium. However, the analgesic …

Skin boosters: Definitions and varied classifications

KH Yi, W Winayanuwattikun, SY Kim… - Skin Research and …, 2024 - Wiley Online Library
Background The concept of “skin boosters” has evolved, marking a shift from traditional uses
of hyaluronic acid (HA) fillers primarily for augmenting skin volume to a more diverse …

[HTML][HTML] MiR-34a enhances chondrocyte apoptosis, senescence and facilitates development of osteoarthritis by targeting DLL1 and regulating PI3K/AKT pathway

W Zhang, P Hsu, B Zhong, S Guo, C Zhang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Osteoarthritis (OA) is the prevalent degenerative disease caused by
various factors. MicroRNAs are important regulators in the inflammation and immune …

[HTML][HTML] Short term analgesic effects of 5% dextrose epidural injections for chronic low back pain: a randomized controlled trial

L Maniquis-Smigel, KD Reeves, HJ Rosen… - … and pain medicine, 2017 - ncbi.nlm.nih.gov
Background Hypertonic dextrose injection (prolotherapy) is reported to reduce pain
including non-surgical chronic low back pain (CLBP), and subcutaneous injection of 5 …