Ion activation methods for peptides and proteins

LA Macias, IC Santos, JS Brodbelt - Analytical chemistry, 2019 - ACS Publications
Mass spectrometry is well-established as one of the primary methods used to characterize
peptides and proteins. New advances in instrumentation and innovative analytical workflows …

Analysis of natural organic matter via fourier transform ion cyclotron resonance mass spectrometry: an overview of recent non‐petroleum applications

Y Qi, P Fu, DA Volmer - Mass Spectrometry Reviews, 2022 - Wiley Online Library
Among the different techniques for mass analysis, ultra‐high‐resolution Fourier transform
ion cyclotron resonance (FTICR) is the method of choice for highly complex samples, as it …

Two-dimensional mass spectrometry: new perspectives for tandem mass spectrometry

MA van Agthoven, YPY Lam, PB O'Connor… - European Biophysics …, 2019 - Springer
Fourier transform ion cyclotron resonance mass analysers (FT-ICR MS) can offer the highest
resolutions and mass accuracies in mass spectrometry. Mass spectra acquired in an FT-ICR …

2D MS/MS spectra recorded in the time domain using repetitive frequency sweeps in linear quadrupole ion traps

LJ Szalwinski, DT Holden, NM Morato… - Analytical …, 2020 - ACS Publications
Ion trap mass spectrometers have emerged as powerful on-site analytical platforms, in spite
of limited mass resolution, due to their compatibility with ambient ionization methods and …

Two-Dimensional Mass Spectrometry Analysis of IgG1 Antibodies

J Paris, TE Morgan, BP Marzullo… - Journal of the …, 2021 - ACS Publications
Two-dimensional mass spectrometry (2DMS) is a new, and theoretically ideal, data-
independent analysis tool, which allows the characterization of a complex mixture and was …

Characterization across a dispersity: polymer mass spectrometry in the second dimension

TE Morgan, CA Wootton, B Marzullo… - Journal of the …, 2021 - ACS Publications
Due to the natural dispersity that is present in synthetic polymers, an added complexity is
always present in the analysis of polymeric species. Tandem mass spectrometry analysis …

Ultra-Accurate Correlation between Precursor and Fragment Ions in Two-Dimensional Mass Spectrometry: Acetylated vs Trimethylated Histone Peptides

M Palasser, SV Heel, MA Delsuc… - Journal of the …, 2023 - ACS Publications
Two-dimensional mass spectrometry (2D MS) is a method for tandem mass spectrometry in
which precursor and fragment ions are correlated by manipulating ion radii rather than by …

Narrowband Modulation Two-Dimensional Mass Spectrometry and Label-Free Relative Quantification of Histone Peptides

M Halper, MA Delsuc, K Breuker… - Analytical …, 2020 - ACS Publications
Two-dimensional mass spectrometry (2D MS) on a Fourier transform ion cyclotron
resonance (FT-ICR) mass analyzer allows for tandem mass spectrometry without requiring …

Two-dimensional tandem mass spectrometry in a single scan on a linear quadrupole ion trap

DT Snyder, LJ Szalwinski, Z St. John… - Analytical …, 2019 - ACS Publications
A two-dimensional tandem mass spectrometry (2D MS/MS) scan has been developed for the
linear quadrupole ion trap. Precursor ions are mass-selectively excited using a nonlinear ac …

Two-Dimensional Fourier Transform Ion Cyclotron Resonance Mass Spectrometry of N-Linked Glycopeptides

RJ Bell, DS Hage, ED Dodds - Journal of the American Society for …, 2024 - ACS Publications
Glycosylation is a common modification across living organisms and plays a central role in
understanding biological systems and disease. Our ability to probe the gylcome has grown …