[HTML][HTML] Mitochondrial-targeted therapy for doxorubicin-induced cardiotoxicity
Anthracyclines, such as doxorubicin, are effective chemotherapeutic agents for the treatment
of cancer, but their clinical use is associated with severe and potentially life-threatening …
of cancer, but their clinical use is associated with severe and potentially life-threatening …
[HTML][HTML] Strategies to prevent anthracycline-induced cardiotoxicity in cancer survivors
Cancer diagnostics and therapies have improved steadily over the last few decades,
markedly increasing life expectancy for patients at all ages. However, conventional and …
markedly increasing life expectancy for patients at all ages. However, conventional and …
[HTML][HTML] Oxidative stress and inflammation: determinants of anthracycline cardiotoxicity and possible therapeutic targets
Chemotherapy with anthracycline-based regimens remains a cornerstone of treatment of
many solid and blood tumors but is associated with a significant risk of cardiotoxicity, which …
many solid and blood tumors but is associated with a significant risk of cardiotoxicity, which …
Repurposing approved drugs for cancer therapy
CH Schein - British Medical Bulletin, 2021 - academic.oup.com
Background Many drugs approved for other indications can control the growth of tumor cells
and limit adverse events (AE). Data sources Literature searches with keywords 'repurposing …
and limit adverse events (AE). Data sources Literature searches with keywords 'repurposing …
[HTML][HTML] Cardioprotective strategies from cardiotoxicity in cancer patients: a comprehensive review
C Kourek, M Touloupaki, A Rempakos, K Loritis… - Journal of …, 2022 - mdpi.com
Cardiotoxicity is a significant complication of chemotherapeutic agents in cancer patients.
Cardiovascular incidents including LV dysfunction, heart failure (HF), severe arrhythmias …
Cardiovascular incidents including LV dysfunction, heart failure (HF), severe arrhythmias …
Exercise and adrenergic regulation of immunity
RJ Simpson, TK Boßlau, C Weyh, GM Niemiro… - Brain, Behavior, and …, 2021 - Elsevier
Exercise training has a profound impact on immunity, exerting a multitude of positive effects
in indications such as immunosenescence, cancer, viral infections and inflammatory …
in indications such as immunosenescence, cancer, viral infections and inflammatory …
Cardiotoxic effect of modern anthracycline dosing on left ventricular ejection fraction: a systematic review and meta‐analysis of placebo arms from randomized …
P Jeyaprakash, S Sangha, K Ellenberger… - Journal of the …, 2021 - Am Heart Assoc
Background Anthracyclines are a key chemotherapeutic agent used against hematological
and solid organ malignancies. However, their benefits in cancer survival are limited by …
and solid organ malignancies. However, their benefits in cancer survival are limited by …
[HTML][HTML] Cardiotoxicity of chemotherapy and targeted agents
TW Mudd Jr, M Khalid, AK Guddati - American Journal of Cancer …, 2021 - ncbi.nlm.nih.gov
The evolution of cancer treatment and development of new classes of anticancer therapies
have continued to revolutionize the field of oncology. New therapies including targeted …
have continued to revolutionize the field of oncology. New therapies including targeted …
[HTML][HTML] Statins to mitigate cardiotoxicity in cancer patients treated with anthracyclines and/or trastuzumab: a systematic review and meta-analysis
M Obasi, A Abovich, JB Vo, Y Gao… - Cancer Causes & …, 2021 - Springer
Abstract Purpose Cardiotoxicity affects 5–16% of cancer patients who receive anthracyclines
and/or trastuzumab. Limited research has examined interventions to mitigate cardiotoxicity …
and/or trastuzumab. Limited research has examined interventions to mitigate cardiotoxicity …
Nanotechnology Approaches for Prevention and Treatment of Chemotherapy‐Induced Neurotoxicity, Neuropathy, and Cardiomyopathy in Breast and Ovarian Cancer …
S Nevins, CD McLoughlin, A Oliveros, JB Stein… - Small, 2023 - Wiley Online Library
Nanotechnology has emerged as a promising approach for the targeted delivery of
therapeutic agents while improving their efficacy and safety. As a result, nanomaterial …
therapeutic agents while improving their efficacy and safety. As a result, nanomaterial …