Research on astronaut health and model organisms have revealed six features of
spaceflight biology that guide our current understanding of fundamental molecular changes …

Postural orthostatic tachycardia syndrome (POTS), the most common form of orthostatic
intolerance in young people, affects approximately 500,000 people in the United States …

This review presents lower body negative pressure (LBNP) as a unique tool to investigate
the physiology of integrated systemic compensatory responses to altered hemodynamic …

The field of human space travel is in the midst of a dramatic revolution. Upcoming missions
are looking to push the boundaries of space travel, with plans to travel for longer distances …

Visual impairment intracranial pressure (VIIP) syndrome is considered an unexplained
major risk for future long-duration spaceflight. NASA recently redefined this syndrome as …

On Earth, humans are subjected to a gravitational force that has been an important
determinant in human evolution and function. During spaceflight, astronauts are subjected to …

Cardiac muscle adapts well to changes in loading conditions. For example, left ventricular
(LV) hypertrophy may be induced physiologically (via exercise training) or pathologically …

Introduction Exposure to microgravity causes alterations in multiple physiological systems,
potentially impacting the ability of astronauts to perform critical mission tasks. The goal of …

Postflight changes in muscle volume, calf muscle transverse relaxation time, and total body
composition were measured in 4 crewmembers after a 17-day mission and in 14–16 …

Abstract Space medicine is fundamental to the human exploration of space. It supports
survival, function and performance in this challenging and potentially lethal environment. It is …