A holistic review on Cryptococcus neoformans

SS Rathore, J Sathiyamoorthy, C Lalitha… - Microbial …, 2022 - Elsevier
Cryptococcus neoformans is an encapsulated fungal pathogen that causes infection in
immunocompromised individuals such as HIV patients, organ transplant patients …

The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

The capsule of Cryptococcus neoformans

A Casadevall, C Coelho, RJB Cordero, Q Dragotakes… - Virulence, 2019 - Taylor & Francis
The capsule of Cryptococcus neoformans is its dominant virulence factor and plays a key
role in the biology of this fungus. In this essay, we focus on the capsule as a cellular …

The 'amoeboid predator-fungal animal virulence'hypothesis

A Casadevall, MS Fu, AJ Guimaraes, P Albuquerque - Journal of Fungi, 2019 - mdpi.com
The observation that some aspects of amoeba-fungal interactions resemble animal
phagocytic cell-fungal interactions, together with the finding that amoeba passage can …

Metabolism in fungal pathogenesis

IV Ene, S Brunke, AJP Brown… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Fungal pathogens must assimilate local nutrients to establish an infection in their
mammalian host. We focus on carbon, nitrogen, and micronutrient assimilation mechanisms …

Adaptation of Cryptococcus neoformans to mammalian hosts: integrated regulation of metabolism and virulence

J Kronstad, S Saikia, ED Nielson, M Kretschmer… - Eukaryotic …, 2012 - Am Soc Microbiol
The basidiomycete fungus Cryptococcus neoformans infects humans via inhalation of
desiccated yeast cells or spores from the environment. In the absence of effective immune …

Unraveling synthesis of the cryptococcal cell wall and capsule

ZA Wang, LX Li, TL Doering - Glycobiology, 2018 - academic.oup.com
Fungal pathogens cause devastating infections in millions of individuals each year,
representing a huge but underappreciated burden on human health. One of these, the …

The transcriptional response of Cryptococcus neoformans to ingestion by Acanthamoeba castellanii and macrophages provides insights into the evolutionary …

LS Derengowski, HC Paes, P Albuquerque… - Eukaryotic …, 2013 - Am Soc Microbiol
Virulence of Cryptococcus neoformans for mammals, and in particular its intracellular style,
was proposed to emerge from evolutionary pressures on its natural environment by …

Overview of selected virulence attributes in Aspergillus fumigatus, Candida albicans, Cryptococcus neoformans, Trichophyton rubrum, and Exophiala dermatitidis

H Boral, B Metin, A Döğen, S Seyedmousavi… - Fungal Genetics and …, 2018 - Elsevier
The incidence of fungal diseases has been increasing since 1980, and is associated with
excessive morbidity and mortality, particularly among immunosuppressed patients. Of the …

Fungal infections of the central nervous system

AA Panackal, PR Williamson - CONTINUUM: Lifelong Learning in …, 2015 - journals.lww.com
Abstract Purpose of Review: This article summarizes current knowledge on the
epidemiology, clinical presentations, diagnosis, and management of selected fungal …