Luteolin alters macrophage polarization to inhibit inflammation

S Wang, M Cao, S Xu, J Shi, X Mao, X Yao, C Liu - Inflammation, 2020 - Springer
Luteolin is a natural flavonoid compound derived from vegetables, fruits, and herbs with
potent anti-inflammatory activity. Macrophage polarization is important in the development …

Associations between gastro-oesophageal reflux disease and a range of diseases: an umbrella review of systematic reviews and meta-analyses

JJ Tan, L Li, X Huang, C Yang, X Liang, Y Zhao, J Xie… - BMJ open, 2020 - bmjopen.bmj.com
Objective Numerous meta-analyses have revealed the association between gastro-
oesophageal reflux disease (GORD) and a range of diseases; however, the certainty of the …

Curcumin inhibits the growth of liver cancer by impairing myeloid‑derived suppressor cells in murine tumor tissues

S Tian, L Liao, Q Zhou, X Huang… - Oncology …, 2021 - spandidos-publications.com
Curcumin, one of the active ingredients of Curcuma longa (Jianghuang), has been reported
to exert multiple bioactivities, including pro‑apoptotic and anti‑inflammatory activities. In …

[HTML][HTML] PHD2 exerts anti-cancer and anti-inflammatory effects in colon cancer xenografts mice via attenuating NF-κB activity

L Wang, Z Niu, X Wang, Z Li, Y Liu, F Luo, X Yan - Life sciences, 2020 - Elsevier
Recent studies suggested that prolyl hydroxylase 2 (PHD2) functions as an important
regulator in vascular inflammation and Streptococcus pneumonia infection. However …

Novel celecoxib-loaded chitosan-fucoidan nanoparticles as potential immunotherapy for oral squamous cell carcinoma: Mechanistic insights

AA Mabrouk, NS El-Mezayen, AK Awaad… - Journal of Drug Delivery …, 2023 - Elsevier
Celecoxib (CXB), a selective COX-2 inhibitor, is a component of triple-oral-metronomic-
chemotherapy. However, chronic CXB utilization in high doses could bring about major …

[HTML][HTML] Baicalin inhibits LPS-induced inflammation in RAW264. 7 cells through miR-181b/HMGB1/TRL4/NF-κB pathway

G Yan, L Chen, H Wang, S Wu, S Li… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Purpose: Inflammation out of control may induce many diseases. Baicalin has certain anti-
inflammatory effects, but its mechanism of action is not clear. Therefore, this study was …

Assessing the causal relationship between 731 immunophenotypes and the risk of lung cancer: a bidirectional mendelian randomization study

M Xu, C Li, L Xiang, S Chen, L Chen, G Ling, Y Hu… - BMC cancer, 2024 - Springer
Background Previous studies have observed a link between immunophenotypes and lung
cancer, both of which are closely associated with genetic factors. However, the causal …

Changes in proteins related to early nerve repair in a rat model of sciatic nerve injury

YS Yuan, F Yu, YJ Zhang, SP Niu, HL Xu… - Neural Regeneration …, 2021 - journals.lww.com
Peripheral nerves have a limited capacity for self-repair and those that are severely
damaged or have significant defects are challenging to repair. Investigating the …

Aging-Accelerated Mouse Prone 8 (SAMP8) mice experiment and network pharmacological analysis of aged Liupao tea aqueous extract in delaying the decline …

W Pan, W Li, H Wu, X Xie, M Xie, Q Nie, Z Liu, S Cai - Antioxidants, 2023 - mdpi.com
Aging and metabolic disorders feedback and promote each other and are closely related to
the occurrence and development of cardiovascular disease, type 2 diabetes …

Exendin-4 intervention attenuates atherosclerosis severity by modulating myeloid-derived suppressor cells and inflammatory cytokines in ApoE-/-mice

M Fu, Q Li, H Qian, X Min, H Yang, Z Liu, W Wu… - International …, 2024 - Elsevier
Objective To investigate the impact of the glucagon-like peptide-1 (GLP-1) receptor agonist
Exendin-4 on the proportion of myeloid-derived suppressor cells (MDSCs) in male ApoE …