Brain development is an extraordinarily complex process achieved through the spatially and
temporally regulated release of key patterning factors. In vitro neurodevelopmental models …

Malformations of cortical development are a group of rare disorders commonly manifesting
with developmental delay, cerebral palsy or seizures. The neurological outcome is …

The mouse brain is the most extensively studied brain of all species. We performed an
exhaustive review of the literature to establish our current state of knowledge on cell …

Some birds achieve primate-like levels of cognition, even though their brains tend to be
much smaller in absolute size. This poses a fundamental problem in comparative and …

Cognition presents evolutionary research with one of its greatest challenges. Cognitive
evolution has been explained at the proximate level by shifts in absolute and relative brain …

Neuronal activity in the brain gives rise to transmembrane currents that can be measured in
the extracellular medium. Although the major contributor of the extracellular signal is the …

It is a widespread notion that the proportion of glial to neuronal cells in the brain increases
with brain size, to the point that glial cells represent “about 90% of all cells in the human …

The neocortex is the seat of higher cognitive functions and, in evolutionary terms, is the
youngest part of the mammalian brain. Since its origin, the neocortex has expanded in …

Neuroscientists have become used to a number of “facts” about the human brain: It has 100
billion neurons and 10-to 50-fold more glial cells; it is the largest-than-expected for its body …

We introduce comparative connectomics, the quantitative study of cross-species
commonalities and variations in brain network topology that aims to discover general …