An Overview on antimalarial peptides: Natural sources, synthetic methodology and biological properties

N Kurniaty, R Maharani, AT Hidayat, U Supratman - Molecules, 2023 - mdpi.com
Peptide compounds play a significant role in medicinal chemistry as they can inhibit the
activity of species that cause malaria. This literature review summarizes the isolation of …

Evolutionary trilogy of malaria, angiotensin II and hypertension: deeper insights and the way forward

A De, A Tiwari, V Pande, A Sinha - Journal of Human Hypertension, 2022 - nature.com
Despite clinical and pathological distinctions between malaria and hypertension,
accumulated epidemiological and evolutionary evidence indicate the need of deeper …

Molecular hybridization strategy for tuning bioactive peptide function

CN Pedron, MDT Torres, CS Oliveira, AF Silva… - Communications …, 2023 - nature.com
The physicochemical and structural properties of antimicrobial peptides (AMPs) determine
their mechanism of action and biological function. However, the development of AMPs as …

Aedes aegypti SGS1 is critical for Plasmodium gallinaceum infection of both the mosquito midgut and salivary glands

BB Kojin, I Martin-Martin, HRC Araújo, B Bonilla… - Malaria journal, 2021 - Springer
Background The invasion of the mosquito salivary glands by Plasmodium sporozoites is a
critical step that defines the success of malaria transmission and a detailed understanding of …

New concepts in malaria pathogenesis: the role of the renin-angiotensin system

LS Silva, JL Silva-Filho, C Caruso-Neves… - Frontiers in cellular …, 2016 - frontiersin.org
Malaria is a worldwide health problem leading the death of millions of people. The disease
is induced by different species of protozoa parasites from the genus Plasmodium. In …

Interaction between bradykinin B2 and Ang-(1–7) Mas receptors regulates erythrocyte invasion by Plasmodium falciparum

L de Souza Silva, D de Barros Peruchetti… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Background The molecular mechanisms involved in erythrocyte invasion by malaria parasite
are well understood, but the contribution of host components is not. We recently reported …

Effect of Captopril on Some Peptides of Renin Angiotensin System (RAS) in Plasmodium berghei-Infected Mice

UR Mahmud, AM Abdulazeez… - … Asian Journal of …, 2019 - science.scholarsacademic.com
Aim: There are conflicting reports on the effect of peptides of the Renin Angiotensin System
(RAS) on the pathogenesis of malaria infection. Captopril is a common antihypertensive …

Parasite clearance in malaria: modelling host and therapy mediated parasite control

D Khoury - 2015 - unsworks.unsw.edu.au
At present malaria is responsible for over half a million deaths annually. Although progress
has been made in controlling this disease, the emergence of drug resistant parasite strains …

[引用][C] Interaction between bradykinin B2 and Ang-(1–7) Mas receptors regulates erythrocyte invasion by Plasmodium falciparum

AT Ferreira-DaSilva, J Perales, C Caruso-Neves… - 2016