The extracellular matrix is an integral and dynamic component of all tissues.
Macromolecular compositions and structural architectures of the matrix are tissue-specific …

Peptides are emerging as a new class of biomaterials due to their unique chemical,
physical, and biological properties. The development of peptide-based biomaterials is …

The coacervation of tropoelastin represents the first major stage of elastic fiber assembly.
The process has been modeled in vitro by numerous studies, initially with mixtures of …

Elastic fibers are an essential component of the extracellular matrix where they provide
structural integrity and elastic recoil in a number of important tissues. A major constituent of …

The interactions of C2C12 myoblasts and human bone marrow stem cells (hMSCs) with silk-
tropoelastin biomaterials, and the capacity of each to promote attachment, proliferation, and …

Elastin enables the reversible deformation of elastic tissues and can withstand decades of
repetitive forces. Tropoelastin is the soluble precursor to elastin, the main elastic protein …

Elastin provides structural integrity, biological cues and persistent elasticity to a range of
important tissues, including the vasculature and lungs. Its critical importance to normal …

Medium-sized and large arteries consist of 3 layers: the tunica intima, tunica media, and
tunica adventitia. The tunica media accounts for the bulk of the vessel wall and is the chief …

Studies over the years have described a filamentous structure to mature elastin that
suggests a complicated packing arrangement of tropoelastin subunits. The currently …

Tissue scaffolds are essential in tissue engineering approaches as they provide a tissue-
mimicking environment for cells, with the aim to promote cell proliferation, cell differentiation …