Most of the genetic variation associated with diabetes, through genome-wide association
studies, does not reside in protein-coding regions, making the identification of functional …

Gene deletion studies have helped reveal the unique and overlapping roles played by IAP
proteins. Crossing IAP mutant mice has helped unravel the complex feed-back regulatory …

Resisting and tolerating microbes are alternative strategies to survive infection, but little is
known about the evolutionary mechanisms controlling this balance. Here genomic analyses …

Aims/hypothesis Exposure to environmental pollution has been consistently linked to
diabetes incidence in humans, but the potential causative mechanisms remain unclear …

A chronic metabolic illness, type 2 diabetes (T2D) is a polygenic and multifactorial
complicated disease. With an estimated 463 million persons aged 20 to 79 having diabetes …

Islet transplantation can restore lost glycemic control in type 1 diabetes subjects but is
restricted in its clinical application by a limiting supply of islets and the need for heavy …

Enterotoxigenic Escherichia coli (ETEC) is an important cause of human and porcine
morbidity and mortality. The current study was conducted to identify intestinal immunity that …

Biomineralization‐controlled exo‐/endoskeleton growth contributes to body growth and
body size diversity. Molluscan shells undergo ectopic biomineralization to form the …

Type 1 diabetes is an autoimmune disease that results from an inflammatory destruction of β-
cells in islets. Mesenchymal stem cells derived from Wharton's jelly (WJ-MSCs) own a …

Avian pathogenic E. coli (APEC) has been detected to cause many acute and chronic
diseases, resulting in huge economic losses to the poultry industry. Previous experiments …