Polymer degradation and drug delivery in PLGA‐based drug–polymer applications: A review of experiments and theories

Y Xu, CS Kim, DM Saylor, D Koo - Journal of biomedical …, 2017 - Wiley Online Library
Poly (lactic‐co‐glycolic acid)(PLGA) copolymers have been broadly used in controlled drug
release applications. Because these polymers are biodegradable, they provide an attractive …

Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment

CD Walkey, WCW Chan - Chemical Society Reviews, 2012 - pubs.rsc.org
Nanomaterials hold promise as multifunctional diagnostic and therapeutic agents. However,
the effective application of nanomaterials is hampered by limited understanding and control …

Magnetic nanoparticles: preparation, physical properties, and applications in biomedicine

A Akbarzadeh, M Samiei, S Davaran - Nanoscale research letters, 2012 - Springer
Finally, we have addressed some relevant findings on the importance of having well-defined
synthetic strategies developed for the generation of MNPs, with a focus on particle formation …

PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect

S Acharya, SK Sahoo - Advanced drug delivery reviews, 2011 - Elsevier
As mortality due to cancer continues to rise, advances in nanotechnology have significantly
become an effective approach for achieving efficient drug targeting to tumour tissues by …

[HTML][HTML] A brief history of long circulating nanoparticles

HB Haroon, AC Hunter, ZS Farhangrazi… - Advanced Drug Delivery …, 2022 - Elsevier
The propensity of the hepatic macrophages (Kupffer cells) to rapidly intercept particulate
materials from the blood has been frustrating in redirecting intravenously injected …

Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles

DE Owens III, NA Peppas - International journal of pharmaceutics, 2006 - Elsevier
The process of opsonization is one of the most important biological barriers to controlled
drug delivery. Injectable polymeric nanoparticle carriers have the ability to revolutionize …

Long-circulating and target-specific nanoparticles: theory to practice

SM Moghimi, AC Hunter, JC Murray - Pharmacological reviews, 2001 - ASPET
The rapid recognition of intravenously injected colloidal carriers, such as liposomes and
polymeric nanospheres from the blood by Kupffer cells, has initiated a surge of development …

The manufacturing techniques of various drug loaded biodegradable poly (lactide-co-glycolide)(PLGA) devices

RA Jain - Biomaterials, 2000 - Elsevier
A considerable research has been conducted on drug delivery by biodegradable polymeric
devices, following the entry of bioresorbable surgical sutures in the market about two …

'Stealth'corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core …

R Gref, M Lück, P Quellec, M Marchand… - Colloids and Surfaces B …, 2000 - Elsevier
Nanoparticles possessing poly (ethylene glycol)(PEG) chains on their surface have been
described as blood persistent drug delivery system with potential applications for …

Synthesis and characterization of PLGA nanoparticles

CE Astete, CM Sabliov - Journal of biomaterials science, polymer …, 2006 - Taylor & Francis
Poly (lactide-co-glycolide)(PLGA) nanoparticles of different physical characteristics (size,
size distribution, morphology, zeta potential) can be synthesized by controlling the …