JAK2 Alterations in Acute Lymphoblastic Leukemia: Molecular Insights for Superior Precision Medicine Strategies

CEJ Downes, BJ McClure, DP McDougal… - Frontiers in Cell and …, 2022 - frontiersin.org
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, arising from
immature lymphocytes that show uncontrolled proliferation and arrested differentiation …

Clinicopathologic characteristics, genetic features, and treatment options for acute lymphoblastic leukemia with JAK2 rearrangement—A 10-case study and literature …

L Zhang, B Shah, Y Zhang, H Tashkandi, W Xiao… - Human Pathology, 2023 - Elsevier
Summary JAK2 rearrangement (JAK2-R) in acute lymphoblastic leukemia (ALL) is rare and
often categorized as B-ALL with BCR:: ABL1–like features based on the World Health …

TLE3 Is a Novel Fusion Partner of JAK2 in Myeloid/Lymphoid Neoplasm With Eosinophilia Responding to JAK2 Inhibition

V Lazarevic, H Lilljebjörn… - Genes …, 2024 - Wiley Online Library
Chromosomal rearrangements involving Janus kinase 2 (JAK2) are rare but recurrent
findings in lymphoid or myeloid neoplasia. Detection of JAK2 fusion genes is important as …

[PDF][PDF] JAK2 in Ph-like B-Acute Lymphoblastic Leukemia.

R Hurtado, F Guirales, J Glaser… - Journal of the Association …, 2023 - researchgate.net
Abstract The Janus Kinase 2 gene (JAK2) provides instructions for generating a protein that
promotes the division and growth, or what is referred to as the proliferation, of cells. This …

[引用][C] Detección de fusiones génicas en datos de secuenciación de RNA en muestras de pacientes con melanoma lentiginoso acral del INCan-México TESIS

ACR VASQUEZ - 2023 - Universidad Nacional Mayor de San …