Neurogenic regions of mammalian brain produce many more neurons that will eventually
survive and reach a mature stage. Developmental cell death affects both embryonically …

Various neurotrophins (NTs), including nerve growth factor, brain-derived neurotrophic
factor, neurotrophin-3, and neurotrophin-4, promote cellular differentiation, survival, and …

Alterations of adult neurogenesis have been reported in several Alzheimer's disease (AD)
animal models and human brains, while defects in this process at presymptomatic/early …

Background The fruiting body of Hericium erinaceus has been demonstrated to possess anti-
dementia activity in mouse model of Alzheimer's disease and people with mild cognitive …

In recent years it has been shown that the therapeutic benefits of human mesenchymal
stem/stromal cells (hMSCs) in the Central Nervous System (CNS) are mainly attributed to …

Neuronal differentiation involves extensive modification of biochemical and morphological
properties to meet novel functional requirements. Reorganization of the mitochondrial …

Neurotrophins (NTs) are members of a neuronal growth factor protein family whose action is
mediated by the tropomyosin receptor kinase (TRK) receptor family receptors and the p75 …

Introduction Nerve growth factor (NGF) is a pleiotropic molecule acting on different cell types
in physiological and pathological conditions. However, the effect of NGF on the survival …

Severe bone defects, especially accompanied by vascular and peripheral nerve injuries,
remain a massive challenge. Most studies related to bone tissue engineering have focused …

Neurotrophins are involved in many physiological and pathological processes in the
nervous system. They regulate and modify signal transduction, transcription and translation …