[HTML][HTML] Polycystic ovary syndrome in insulin-resistant adolescents with obesity: the role of nutrition therapy and food supplements as a strategy to protect fertility

V Calcaterra, E Verduci, H Cena, VC Magenes… - Nutrients, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in young
reproductive-aged women. PCOS is often associated with obesity and impairs reproductive …

The role of glp-1 receptor agonists in insulin resistance with concomitant obesity treatment in polycystic ovary syndrome

K Bednarz, K Kowalczyk, M Cwynar, D Czapla… - International journal of …, 2022 - mdpi.com
Insulin resistance is documented in clamp studies in 75% of women with polycystic ovary
syndrome (PCOS). Although it is not included in the diagnostic criteria of PCOS, there is a …

The obese brain: mechanisms of systemic and local inflammation, and interventions to reverse the cognitive deficit

V Salas-Venegas, RP Flores-Torres… - Frontiers in Integrative …, 2022 - frontiersin.org
Overweight and obesity are now considered a worldwide pandemic and a growing public
health problem with severe economic and social consequences. Adipose tissue is an organ …

Hypothalamic mechanisms of obesity-associated disturbance of hypothalamic–pituitary–ovarian axis

X Chen, Z Xiao, Y Cai, L Huang, C Chen - Trends in endocrinology & …, 2022 - cell.com
Ovulatory disorders are the most common clinical feature exhibited among obese women.
Initiation of ovulation physiologically requires a surge of gonadotropin-releasing hormone …

Clinical application of aromatase inhibitors to treat male infertility

C Yang, P Li, Z Li - Human Reproduction Update, 2022 - academic.oup.com
BACKGROUND Infertility affects 15% of men and contributes to nearly half of all cases of
infertility. Infertile men usually have impaired spermatogenesis, presenting as azoospermia …

Computational analysis of eugenol inhibitory activity in lipoxygenase and cyclooxygenase pathways

F Das Chagas Pereira de Andrade, AN Mendes - Scientific reports, 2020 - nature.com
Chronic inflammation is triggered by numerous diseases such as osteoarthritis, Crohn's
disease and cancer. The control of the pro-inflammatory process can prevent, mitigate …

[HTML][HTML] Association of leptin with obesity and insulin resistance

R Kumar, K Mal, MK Razaq, M Magsi, MK Memon… - Cureus, 2020 - ncbi.nlm.nih.gov
Methods This case-control study was conducted in a tertiary care hospital in Pakistan from
January 2020 to April 2020. Ninety-two participants with BMI greater than 25 kg/m 2, with no …

Association between body mass index and female infertility in the United States: data from National Health and Nutrition Examination Survey 2013–2018

L Zhu, B Zhou, X Zhu, F Cheng, Y Pan… - … journal of general …, 2022 - Taylor & Francis
Purpose This study aimed to investigate the effects of body mass index (BMI) on infertility in
women of childbearing age. Patients and Methods We performed a cross-sectional study …

Probiotics and polycystic ovary syndrome: a perspective for management in adolescents with obesity

V Calcaterra, V Rossi, G Massini, F Casini, G Zuccotti… - Nutrients, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) affects a considerable percentage of females of
reproductive age. PCOS is an obesity-related condition and its effects are greatly amplified …

Mitofusins: from mitochondria to fertility

S Zhao, N Heng, H Wang, H Wang, H Zhang… - Cellular and Molecular …, 2022 - Springer
Germ cell formation and embryonic development require ATP synthesized by mitochondria.
The dynamic system of the mitochondria, and in particular, the fusion of mitochondria, are …